Comparison between the mRNA distributions the bursty model and the three-stage model with a cell volume description.

The blue (red) dots show the simulated mRNA concentration (copy number) distribution for the three-stage model with a cell volume description obtained from SSA. The blue (red) curves show the simulated mRNA concentration (copy number) distribution for the bursty model with a cell volume description obtained from SSA. The parameters for the three-stage model are chosen as N0 = 0.2N, β = 1, κ = 2, α0 = α1 = 1, v = 10f, d = f, s = 0.2r, u = v. The parameters for the bursty model are chosen as N0 = 0.2N, B = 0.2, β = 1, κ = 2, α0 = α1 = 1, v = 10f, where v is the degradation rate of mRNA. The growth rate g is determined so that f = 2 for the bursty model. The parameter ρ and a are chosen so that the mean mRNA number 〈n〉 = 25 and the mean cell volume 〈V〉 = 1 for the bursty model. (EPS)