The physiological and pathological development of the breast is strongly affected by the hormonal milieu consisting of steroid hormones. Mass spectrometry (MS) technologies of high sensitivity and specificity enable the quantification of androgens and consequently the characterization of the hormonal status. The aim of this study is the assessment of plasma androgens and androgen glucuronides, in the par excellence hormone-sensitive tissue of the breast, through the application of liquid chromatography-mass spectrometry (LC-MS). A simple and efficient fit-for-purpose method for the simultaneous identification and quantification of dehydroepiandrosterone sulfate (DHEAS), androstenedione (A4), androsterone glucuronide (ADTG) and androstane-3α...
Objective: The measurement of serum testosterone in women is challenging due to lack of trueness, pr...
Steroid hormones are crucial substances that mediate a wide range of vital physiological functions o...
Steroid analysis in clinical laboratories is dominated by immunoassays (IAs) that have a high sample...
Objectives: To develop a robust liquid chromatography-tandem mass spectrometry (LC–MS/MS) method to ...
BACKGROUND: Measurement of serum androgens is im-portant in adult, geriatric, pediatric endocrinolog...
Disease-specific compounds (biomarkers) are analyzed in clinical laboratories to assist with diagnos...
11-Oxygenated androgens (11-OAs) are being discussed as potential biomarkers in diagnosis and therap...
thesisDehydroepiandrosterone and androstenedione are precursors of sex hormones; testosterone is a b...
Background: With liquid chromatography-tandem mass spectrometry (LC-MS/MS) increasingly being used f...
Prostate cancer is the most common malignancy among men in the Western world. Treatment of this pati...
Anti-doping rule violations related to the abuse of endogenous anabolic androgenic steroids can be c...
The aim of the current research was to develop a simple and rapid mass spectrometry-based assay for ...
Latest advances in LC-MS/MS technology have changed the field of steroid hormone analysis. Steroid h...
In the context of hormonal contraception and hormone replacement therapy (HRT), many women are expos...
Liquid chromatography, coupled with tandem mass spectrometry, presents a powerful tool for the quant...
Objective: The measurement of serum testosterone in women is challenging due to lack of trueness, pr...
Steroid hormones are crucial substances that mediate a wide range of vital physiological functions o...
Steroid analysis in clinical laboratories is dominated by immunoassays (IAs) that have a high sample...
Objectives: To develop a robust liquid chromatography-tandem mass spectrometry (LC–MS/MS) method to ...
BACKGROUND: Measurement of serum androgens is im-portant in adult, geriatric, pediatric endocrinolog...
Disease-specific compounds (biomarkers) are analyzed in clinical laboratories to assist with diagnos...
11-Oxygenated androgens (11-OAs) are being discussed as potential biomarkers in diagnosis and therap...
thesisDehydroepiandrosterone and androstenedione are precursors of sex hormones; testosterone is a b...
Background: With liquid chromatography-tandem mass spectrometry (LC-MS/MS) increasingly being used f...
Prostate cancer is the most common malignancy among men in the Western world. Treatment of this pati...
Anti-doping rule violations related to the abuse of endogenous anabolic androgenic steroids can be c...
The aim of the current research was to develop a simple and rapid mass spectrometry-based assay for ...
Latest advances in LC-MS/MS technology have changed the field of steroid hormone analysis. Steroid h...
In the context of hormonal contraception and hormone replacement therapy (HRT), many women are expos...
Liquid chromatography, coupled with tandem mass spectrometry, presents a powerful tool for the quant...
Objective: The measurement of serum testosterone in women is challenging due to lack of trueness, pr...
Steroid hormones are crucial substances that mediate a wide range of vital physiological functions o...
Steroid analysis in clinical laboratories is dominated by immunoassays (IAs) that have a high sample...