Abstract Background In the perspective of ART-free HIV remission, vertically infected children treated with suppressive ART from early infancy represent an optimal population model to better understand the genetic complexity of the reservoir. Objectives To evaluate the proportion of defective viral population and the genotypic resistance patterns in cell-associated HIV DNA. Methods In a cohort including 93 ART-treated vertically HIV-infected (VHIV) children in Mali with plasma HIV-1 RNA ≤q50\,copies/mL for at least 6\,months, we studied total HIV DNA, percentage of defective genomes and resistance by reverse transcriptase and protease bulk sequencing from whole blood in dried blood spots. Results Children had a median age of 9.9\,years at t...
The objectives of this study were to describe the pretreatment HIV-1 DNA concentrations in children ...
M. Med. Sc. University of KwaZulu-Natal, Durban 2014.Background Better understanding of drug resist...
With limited and low-genetic barrier drugs used for the prevention of mother-to-child transmission (...
Abstract Background In the perspective of ART-free HIV remission, vertically infected children treat...
Introduction Globally, HIV-related adolescent deaths have increased about 50%, especially for those ...
International audienceBackground: Absence of detectable viraemia after treatment cessation in some v...
Absence of detectable HIV viremia treatment cessation in 3 children suggests that very early could l...
Introduction The success of antiretroviral therapy (ART) has changed HIV from a deadly to a chronic ...
International audienceObjectives: To evaluate the virological response and to describe the resistanc...
Treatment of HIV-1 infection with highly active antiretroviral therapy has led to sustained viral su...
International audienceIntroduction: The emergence of HIV-1 recombinant forms and drug combined antir...
Background: Drug resistance mutations affect antiretroviral therapy (ART) effectiveness in HIV-1-inf...
Background: Drug resistance mutations (DRMs) increasingly jeopardize paediatric HIV programmes in su...
Background: Future strategies aiming to achieve HIV-1 remission are likely to target individuals wit...
The objectives of this study were to describe the pretreatment HIV-1 DNA concentrations in children ...
M. Med. Sc. University of KwaZulu-Natal, Durban 2014.Background Better understanding of drug resist...
With limited and low-genetic barrier drugs used for the prevention of mother-to-child transmission (...
Abstract Background In the perspective of ART-free HIV remission, vertically infected children treat...
Introduction Globally, HIV-related adolescent deaths have increased about 50%, especially for those ...
International audienceBackground: Absence of detectable viraemia after treatment cessation in some v...
Absence of detectable HIV viremia treatment cessation in 3 children suggests that very early could l...
Introduction The success of antiretroviral therapy (ART) has changed HIV from a deadly to a chronic ...
International audienceObjectives: To evaluate the virological response and to describe the resistanc...
Treatment of HIV-1 infection with highly active antiretroviral therapy has led to sustained viral su...
International audienceIntroduction: The emergence of HIV-1 recombinant forms and drug combined antir...
Background: Drug resistance mutations affect antiretroviral therapy (ART) effectiveness in HIV-1-inf...
Background: Drug resistance mutations (DRMs) increasingly jeopardize paediatric HIV programmes in su...
Background: Future strategies aiming to achieve HIV-1 remission are likely to target individuals wit...
The objectives of this study were to describe the pretreatment HIV-1 DNA concentrations in children ...
M. Med. Sc. University of KwaZulu-Natal, Durban 2014.Background Better understanding of drug resist...
With limited and low-genetic barrier drugs used for the prevention of mother-to-child transmission (...