Additional file 9 of Functional changes in the oral microbiome after use of fluoride and arginine containing dentifrices: a metagenomic and metatranscriptomic study

Additional file 9: Additional Figure 8. Changes in bacterial communities’ gene content and activity after Fluoride treatment. Each dot represents a gene that was significantly under- or over-represented in the metagenomics (MTG) or metatranscriptomic (MTT) datasets after 3-month use of fluoride dentifrice. The abundance/expression level in the MTG/MTT datasets (expressed as the number of reads normalized per gene length per Mpb of sequencing coverage) and the fold change (RLM before/RLM after) are shown for each gene. Dots corresponding to genes over-represented in baseline are colored in blue and those over-represented after Fluoride treatment are depicted in orange. Genes differentially represented in caries-active sites (CA) and Caries-free individuals (CF) are shown at the top and lower panels, respectively