Add to ORKGThe potential of a sustained release formulation for paracetamol produced by melt pelletisation was investigated. The chosen formulation was based on the combination of stearic acid as a melting binder and anhydrous lactose as a filler. After determination of the size distribution, the pellet characterisation included scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), specific surface area and true density determination. Hence, the in vitro release from every single size fraction (2000, 1250, 800, 630, <630 microm) was evaluated and the release mechanism was analysed with the help of an appropriate mathematical model. The results of drug content and superficial atomic composition were found to be constant in all pel...
Paracetamol of different particle-size ranges was incorporated into glyceryl monostearate (GMS) gran...
Paracetamol/Eudragit RS, paracetamol/ethylcellulose, and paracetamol/cellulose acetate pellets of di...
Objective - A process of melt granulation whereby the drug powder is mixed with a melted wax has bee...
The potential of a sustained release formulation for paracetamol produced by melt pelletisation was ...
The potential of a sustained release formulation for paracetamol produced by melt pelletisation was ...
The potential of a sustained release formulation for paracetamol produced by melt pelletisation was ...
The purpose of this study is to evaluate the possibility of developing a cylindrical sustained-relea...
With the purpose of evaluating the behavior of different polymers employed as binders in small-diame...
This study was conducted to develop and characterize a hot melt co-extruded cylindrical system for c...
A sustained release dosage form is suggested based on the advantages of tablets and pellets produced...
Objective: To study the effects of three formulation variables (PVP, stearic acid and Avicel PH101) ...
Drug dissolution and release characteristics from freeze-dried wafers and solvent-cast films prepare...
Multi-particulate tablets have the advantages of pellets and those of tablets. Formulation studies w...
An attempt has been made to establish relationships between drug solubility, drug level, filler solu...
Paracetamol of different particle-size ranges was incorporated into glyceryl monostearate (GMS) gran...
Paracetamol/Eudragit RS, paracetamol/ethylcellulose, and paracetamol/cellulose acetate pellets of di...
Objective - A process of melt granulation whereby the drug powder is mixed with a melted wax has bee...
The potential of a sustained release formulation for paracetamol produced by melt pelletisation was ...
The potential of a sustained release formulation for paracetamol produced by melt pelletisation was ...
The potential of a sustained release formulation for paracetamol produced by melt pelletisation was ...
The purpose of this study is to evaluate the possibility of developing a cylindrical sustained-relea...
With the purpose of evaluating the behavior of different polymers employed as binders in small-diame...
This study was conducted to develop and characterize a hot melt co-extruded cylindrical system for c...
A sustained release dosage form is suggested based on the advantages of tablets and pellets produced...
Objective: To study the effects of three formulation variables (PVP, stearic acid and Avicel PH101) ...
Drug dissolution and release characteristics from freeze-dried wafers and solvent-cast films prepare...
Multi-particulate tablets have the advantages of pellets and those of tablets. Formulation studies w...
An attempt has been made to establish relationships between drug solubility, drug level, filler solu...
Paracetamol of different particle-size ranges was incorporated into glyceryl monostearate (GMS) gran...
Paracetamol/Eudragit RS, paracetamol/ethylcellulose, and paracetamol/cellulose acetate pellets of di...
Objective - A process of melt granulation whereby the drug powder is mixed with a melted wax has bee...