AIM: This was a phase II study to assess the activity of a novel neoadjuvant regimen in locally-advanced breast cancer. PATIENTS AND METHODS: Fifty patients with histological confirmation of locally advanced breast cancer received treatment with gemcitabine 1000 mg/m(2) (day 1) followed by gemcitabine 800 mg/m(2) plus docetaxel 75 mg/m(2) plus pegylated liposomal doxorubicin (PLD) 30 mg/m(2) (day 8) every 3 weeks for at least 4 cycles, plus a final 2 additional cycles. Tumour size was T1 (n=2), T2 (n=32), T3 (n=14), T4 (n=2). All 50 patients underwent surgery. RESULTS: Clinical complete, partial and no response were observed in 13 (26%), 24 (48%) and 11 (22%) patients, respectively (overall response rate: 74%). The number of chemother...
BACKGROUND: Lapatinib is an effective anti-HER2 therapy in advanced breast cancer and docetaxel is o...
Background: Neoadjuvant anthracycline- and taxane-based chemotherapy is frequently administered in b...
Background: The aim of this study was to determine the activity and safety of pegylated liposomal do...
Background: Neoadjuvant chemotherapy with concurrent docetaxel, doxorubicin and cyclophosphamide is ...
Background: Neoadjuvant chemotherapy has a sound rationale for use in women with large operable brea...
Background: Neoadjuvant chemotherapy has a sound rationale for use in women with large operable brea...
BACKGROUND: we previously reported a phase I trial of liposome-encapsulated doxorubicin citrate (LD...
Purpose: To explore the activity of pegylated liposomal doxorubicin (PLD) as neoadjuvant therapy of ...
Background: docetaxel (T), capecitabine (X), and cisplatin ( P) are active chemotherapy for patients...
Abstract This phase I/II neoadjuvant trial (ClinicalTrials.gov identifier NCT00066443)...
Abstract This phase I/II neoadjuvant trial (ClinicalTrials.gov identifier NCT00066443)...
Breast cancer is a global issue regarding women’s health, and high incident rates remain in the Taiw...
Abstract This phase I/II neoadjuvant trial (ClinicalTrials.gov identifier NCT00066443)...
Abstract BACKGROUND: This study was designed to determine whether delivering neo-adjuvant chemothera...
Objective To evaluate the efficacy and safety of the combination of pegylated liposomal doxorubicin ...
BACKGROUND: Lapatinib is an effective anti-HER2 therapy in advanced breast cancer and docetaxel is o...
Background: Neoadjuvant anthracycline- and taxane-based chemotherapy is frequently administered in b...
Background: The aim of this study was to determine the activity and safety of pegylated liposomal do...
Background: Neoadjuvant chemotherapy with concurrent docetaxel, doxorubicin and cyclophosphamide is ...
Background: Neoadjuvant chemotherapy has a sound rationale for use in women with large operable brea...
Background: Neoadjuvant chemotherapy has a sound rationale for use in women with large operable brea...
BACKGROUND: we previously reported a phase I trial of liposome-encapsulated doxorubicin citrate (LD...
Purpose: To explore the activity of pegylated liposomal doxorubicin (PLD) as neoadjuvant therapy of ...
Background: docetaxel (T), capecitabine (X), and cisplatin ( P) are active chemotherapy for patients...
Abstract This phase I/II neoadjuvant trial (ClinicalTrials.gov identifier NCT00066443)...
Abstract This phase I/II neoadjuvant trial (ClinicalTrials.gov identifier NCT00066443)...
Breast cancer is a global issue regarding women’s health, and high incident rates remain in the Taiw...
Abstract This phase I/II neoadjuvant trial (ClinicalTrials.gov identifier NCT00066443)...
Abstract BACKGROUND: This study was designed to determine whether delivering neo-adjuvant chemothera...
Objective To evaluate the efficacy and safety of the combination of pegylated liposomal doxorubicin ...
BACKGROUND: Lapatinib is an effective anti-HER2 therapy in advanced breast cancer and docetaxel is o...
Background: Neoadjuvant anthracycline- and taxane-based chemotherapy is frequently administered in b...
Background: The aim of this study was to determine the activity and safety of pegylated liposomal do...