Microgeographic variation of Y-chromosome haplotypes in Italy

Within an Italian collaborative exercise on the extended haplotype of the Y-chromosome, 1288 subjects were typed by the AmpFlSTR YFiler Amplification Kit (AB Applied Biosystems) and other 526 were typed by the PowerPlex Y1 System (Promega). The sampling scheme included either a \u2018\u2018regional\u2019\u2019 or a \u2018\u2018local\u2019\u2019 recruitment, the first referring to individuals born in the region of the participating lab, the second referring to individuals coming from small villages. Total sample sizes were N = 954 and 860, respectively. A significant decrease of haplotype diversity was found in the local samples. The results may be of interest in forensic applications of the Y-chromosome