In malignancies, cellular senescence is critical for carcinogenesis, development, and immunological regulation. Patients with acute myeloid leukemia (AML) have not investigated a reliable cellular senescence-associated profile and its significance in outcomes and therapeutic response. Cellular senescence-related genes were acquired from the CellAge database, while AML data were obtained from the GEO and TCGA databases. The TCGA-AML group served as a training set to construct a prognostic risk score signature, while the GSE71014 set was used as a testing set to validate the accuracy of the signature. Through exploring the expression profiles of cellular senescence-related genes (SRGs) in AML patients, we used Lasso and Cox regression analysi...
IntroductionThe heterogeneity of treatment response in acute myeloid leukemia (AML) patients poses g...
BackgroundAs a severe hematological malignancy in adults, acute myeloid leukemia (AML) is characteri...
BackgroundCellular senescence plays an irreplaceable role in tumorigenesis, progression, and tumor m...
In malignancies, cellular senescence is critical for carcinogenesis, development, and immunological ...
In malignancies, cellular senescence is critical for carcinogenesis, development, and immunological ...
Background and methods: The functional and transcriptional features of immune effector senescence an...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has an unfavo...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
We have recently shown that bone marrow (BM) RNA profiles stratify patients with acute myeloid leuke...
BackgroundAs a severe hematological malignancy in adults, acute myeloid leukemia (AML) is characteri...
IntroductionThe heterogeneity of treatment response in acute myeloid leukemia (AML) patients poses g...
BackgroundAs a severe hematological malignancy in adults, acute myeloid leukemia (AML) is characteri...
BackgroundCellular senescence plays an irreplaceable role in tumorigenesis, progression, and tumor m...
In malignancies, cellular senescence is critical for carcinogenesis, development, and immunological ...
In malignancies, cellular senescence is critical for carcinogenesis, development, and immunological ...
Background and methods: The functional and transcriptional features of immune effector senescence an...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has an unfavo...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
Immune genes play an important role in the development and progression of acute myeloid leukemia (AM...
We have recently shown that bone marrow (BM) RNA profiles stratify patients with acute myeloid leuke...
BackgroundAs a severe hematological malignancy in adults, acute myeloid leukemia (AML) is characteri...
IntroductionThe heterogeneity of treatment response in acute myeloid leukemia (AML) patients poses g...
BackgroundAs a severe hematological malignancy in adults, acute myeloid leukemia (AML) is characteri...
BackgroundCellular senescence plays an irreplaceable role in tumorigenesis, progression, and tumor m...