Metabolic profile comparison of GF, OligoMM12, and SPF C57B6/J mice by UPLC/MS in liver.
- Daniel Hoces (4353634)
- Jiayi Lan (4875301)
- Wenfei Sun (8967236)
- Tobias Geiser (13833473)
- Melanie L. Stäubli (13833476)
- Elisa Cappio Barazzone (13833479)
- Markus Arnoldini (141879)
- Tenagne D. Challa (9039659)
- Manuel Klug (13833482)
- Alexandra Kellenberger (13833485)
- Sven Nowok (13833488)
- Erica Faccin (24363)
- Andrew J. Macpherson (9185226)
- Bärbel Stecher (78807)
- Shinichi Sunagawa (125995)
- Renato Zenobi (248557)
- Wolf-Dietrich Hardt (46235)
- Christian Wolfrum (548967)
- Emma Slack (132778)
Publication date
September 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
Manually curated list of compounds obtained by targeted peak extraction from differentially expressed pathways in liver samples during the light phase (ZT 5) and dark phase (ZT 16). p-values obtained by Tukey’s honest significance test after log2 transformation of area value. Number of mice per group: ZT5: GF = 4, OligoMM12 = 6, SPF = 7; ZT16: GF = 4, OligoMM12 = 6, SPF = 7. Data underlying this figure are supplied in S1 Data. GF, germ-free; SPF, specific-opportunistic-pathogen-free; UPLC/MS, ultraperformance liquid chromatography coupled with mass spectrometry; ZT, Zeitgeber time. (TIF)</p
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