Confirmation of shared genes within differential expression analysis taking tissue effects into account.

The upper dark grey circle contains the nine genes identified as being either commonly over, or under, expressed simultaniously within dogs and tame foxes using filter levels the 95th and 97th percentiles whilst only accounting for condition (wolves vs. dogs and aggressive vs. tame fox). Six of these genes (RGR, CHRNA5, MYO7A, TRIB2, STMND1 and OASL) are present when DESeq2 is run whilst also accounting for differences in tissue (light grey left oval). SQLE, ARHGAP25 and ITGA7 are observed only within the differentially expressed transcript list that is based solely on condition (dark grey right oval). (TIF)