The videos show Calcium influx, using a Ca sensitive dye, into pulmonary microvascular endothelial cells following the onset of shear stress and its modulation by knocking down the mechanosensitive ion channel Piezo2.</p
The activation of endothelial cells by endothelium-dependent vasodilators has been investigated usin...
Arterial blood pressure is controlled by vasodilatory factors such as nitric oxide (NO) that are rel...
Piezo1 channels are newly discovered ion channels which have come to the fore as players in endothel...
The mechanisms by which physical forces regulate endothelial cells to determine the complexities of ...
Mechanical forces are translated into biochemical stimuli by mechanotransduction channels, such as t...
Mechanosensitive ion channels mediate endothelial responses to blood flow and orchestrate their phys...
In intrapulmonary artery (IPA), endothelial cells (EC) respond to mechanical stimuli by releasing va...
Shear stress is the major mechanical force applied on vascular endothelial cells by blood flow, and ...
The extravasation of leukocytes is a critical step during inflammation that requires the localized o...
Shear stress exerted by the blood stream modulates endothelial functions through altering gene expre...
Mechanosensation is perhaps the last sensory modality not understood at the molecular level. Ion cha...
Endothelial cells (ECs) line the lumen of the cardiovascular system and serve as a regulatory barrie...
Regulation of Ca2+ entry plays important roles in cardiovascular physiology and pathophysiology. Und...
The endothelium is an interconnected network upon which hemodynamic mechanical forces act to control...
Elevation of intracellular Ca2+ ([Ca2+]i) is essential for platelet function. Despite the establishe...
The activation of endothelial cells by endothelium-dependent vasodilators has been investigated usin...
Arterial blood pressure is controlled by vasodilatory factors such as nitric oxide (NO) that are rel...
Piezo1 channels are newly discovered ion channels which have come to the fore as players in endothel...
The mechanisms by which physical forces regulate endothelial cells to determine the complexities of ...
Mechanical forces are translated into biochemical stimuli by mechanotransduction channels, such as t...
Mechanosensitive ion channels mediate endothelial responses to blood flow and orchestrate their phys...
In intrapulmonary artery (IPA), endothelial cells (EC) respond to mechanical stimuli by releasing va...
Shear stress is the major mechanical force applied on vascular endothelial cells by blood flow, and ...
The extravasation of leukocytes is a critical step during inflammation that requires the localized o...
Shear stress exerted by the blood stream modulates endothelial functions through altering gene expre...
Mechanosensation is perhaps the last sensory modality not understood at the molecular level. Ion cha...
Endothelial cells (ECs) line the lumen of the cardiovascular system and serve as a regulatory barrie...
Regulation of Ca2+ entry plays important roles in cardiovascular physiology and pathophysiology. Und...
The endothelium is an interconnected network upon which hemodynamic mechanical forces act to control...
Elevation of intracellular Ca2+ ([Ca2+]i) is essential for platelet function. Despite the establishe...
The activation of endothelial cells by endothelium-dependent vasodilators has been investigated usin...
Arterial blood pressure is controlled by vasodilatory factors such as nitric oxide (NO) that are rel...
Piezo1 channels are newly discovered ion channels which have come to the fore as players in endothel...
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