Bacterial microcompartments enclose a biochemical pathway and reactive intermediate within a protein envelope formed by the shell proteins. Herein, the orientation of the propanediol-utilization (Pdu) microcompartment shell protein PduA in bacterial microcompartments and in synthetic nanotubes, and the orientation of PduB in synthetic nanotubes are revealed. When produced individually, PduA hexamers and PduB trimers, tessellate to form flat sheets in the crystal, or they can self-assemble to form synthetic protein nanotubes in solution. Modelling the orientation of PduA in the 20 nm nanotube so as to preserve the shape complementarity and key interactions seen in the crystal structure suggests that the concave surface of the PduA hexamer fa...
An ability to design peptide-based nanotubes (PNTs) rationally with defined and mutable internal cha...
Propanediol metabolism in Citrobacter freundii occurs within a metabolosome, a subcellular proteinac...
Nanotubular structures can form from a variety of different materials such as inorganic19–22, carbon...
Bacterial microcompartments enclose a biochemical pathway and reactive intermediate within a protein...
Bacterial microcompartments are large proteinaceous assemblies that are found in the cytoplasm of so...
Background: PduA is a major shell protein in 1,2-propanediol utilization micro compartments. Results...
Many bacteria use protein-based organelles known as bacterial microcompartments (BMCs) to organize a...
Many bacteria use protein-based organelles known as bacterial microcompartments (BMCs) to organize a...
We report a structural characterization of self-assembling nanostructures. Using atomic force micros...
Bacterial microcompartments (BMCs) are polyhedral, protein-based organelles present in a wide range ...
Proteins are macromolecules with characteristic structures and biological functions. It is extremely...
Self-assembly of proteins, peptides and DNA is a powerful approach for fabricating novel supramolecu...
Living systems utilize proteins as building blocks to construct a large variety of self-assembled na...
Bacterial microcompartments (BMC) are complex macromolecular assemblies that participate to varied c...
Bin/Amphiphysin/Rvs (BAR) domain proteins control the curvature of lipid membranes in endocytosis, t...
An ability to design peptide-based nanotubes (PNTs) rationally with defined and mutable internal cha...
Propanediol metabolism in Citrobacter freundii occurs within a metabolosome, a subcellular proteinac...
Nanotubular structures can form from a variety of different materials such as inorganic19–22, carbon...
Bacterial microcompartments enclose a biochemical pathway and reactive intermediate within a protein...
Bacterial microcompartments are large proteinaceous assemblies that are found in the cytoplasm of so...
Background: PduA is a major shell protein in 1,2-propanediol utilization micro compartments. Results...
Many bacteria use protein-based organelles known as bacterial microcompartments (BMCs) to organize a...
Many bacteria use protein-based organelles known as bacterial microcompartments (BMCs) to organize a...
We report a structural characterization of self-assembling nanostructures. Using atomic force micros...
Bacterial microcompartments (BMCs) are polyhedral, protein-based organelles present in a wide range ...
Proteins are macromolecules with characteristic structures and biological functions. It is extremely...
Self-assembly of proteins, peptides and DNA is a powerful approach for fabricating novel supramolecu...
Living systems utilize proteins as building blocks to construct a large variety of self-assembled na...
Bacterial microcompartments (BMC) are complex macromolecular assemblies that participate to varied c...
Bin/Amphiphysin/Rvs (BAR) domain proteins control the curvature of lipid membranes in endocytosis, t...
An ability to design peptide-based nanotubes (PNTs) rationally with defined and mutable internal cha...
Propanediol metabolism in Citrobacter freundii occurs within a metabolosome, a subcellular proteinac...
Nanotubular structures can form from a variety of different materials such as inorganic19–22, carbon...