Assessing a sustainable manufacturing route to lapatinib
- Stark, RT
- Pye, D
- Chen, W
- Newton, OJ
- Deadman, BJ
- Miller, P
- Panayides, J-L
- Riley, DL
- Hellgardt, K
- Hii, KKM
Publication date
August 2022
DOI Publisher
Royal Society of Chemistry (RSC) Journal
Reaction Chemistry & EngineeringAbstract
A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the sustainability of the key steps of the reaction
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