Bacterial burden of infected implants.
- David B. Huang (8155570)
- Kimberly M. Brothers (13813223)
- Jonathan B. Mandell (13813226)
- Masashi Taguchi (13813229)
- Peter G. Alexander (5536403)
- Dana M. Parker (13813232)
- Dean Shinabarger (2947098)
- Chris Pillar (13813235)
- Ian Morrissey (336933)
- Stephen Hawser (13813238)
- Parviz Ghahramani (13813241)
- Despina Dobbins (13813244)
- Nicholas Pachuda (13813247)
- Ronald Montelaro (13813250)
- Jonathan D. Steckbeck (13813253)
- Kenneth L. Urish (13813256)
Publication date
September 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
Ex vivo analysis of PLG0206 was performed by removing the infected implant at 2 days post infection and treating with 1 mg/mL PLG0206 for 15 min. Compared with implants from PBS vehicle (I&D alone) (n = 4), implants treated with PLG0206 (n = 5) displayed significantly reduced S. aureus biofilm burden. Data are mean (standard deviation). Mann-Whitney statistical analysis was performed using GraphPad Prism version 9. *P = 0.016. CFU, colony-forming units; I&D, irrigation and debridement; PBS, phosphate-buffered saline. (EPS)</p
Extracted data
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