Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy: population based retrospective cohort study.
- Fell, Deshayne B
- Dimanlig-Cruz, Sheryll
- Regan, Annette K
- Håberg, Siri E
- Gravel, Christopher A
- Oakley, Laura
- Alton, Gillian D
- Török, Eszter
- Dhinsa, Tavleen
- Shah, Prakesh S
- Wilson, Kumanan
- Sprague, Ann E
- El-Chaâr, Darine
- Walker, Mark C
- Barrett, Jon
- Okun, Nannette
- Buchan, Sarah A
- Kwong, Jeffrey C
- Wilson, Sarah E
- Dunn, Sandra I
- MacDonald, Shannon E
- Dougan, Shelley D
DOIAbstract
OBJECTIVE: To assess the risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy. DESIGN: Population based retrospective cohort study. SETTING: Ontario, Canada, 1 May to 31 December 2021. PARTICIPANTS: All liveborn and stillborn infants from pregnancies conceived at least 42 weeks before the end of the study period and with gestational age ≥20 weeks or birth weight ≥500 g. MAIN OUTCOME MEASURES: Using Cox regression, hazard ratios and 95% confidence intervals were estimated for preterm birth before 37 weeks (overall and spontaneous preterm birth), very preterm birth (<32 weeks), small for gestational age at birth (<10th centile), and stillbirth. Vaccination against covid-19 was t...
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