(A) Heatmap showing fold change of RHOH gene expression in human neutrophils treated with GM-CSF at different time points (compared with freshly isolated neutrophils). The underlying data can be found in S1 Data. (B) Violin plots showing RHOH gene expression in cell populations identified in COVID-19 patients. Mono, monocytes; NK, natural killer cells; Macro, macrophages; Epi, epithelial cells; Neu, neutrophils, shown in black box (□); DC, dendritic cells; Plasma, plasma B cells; Mega, megakaryocytes. The underlying data can be found in https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE158055. (C) Violin plots showing the expression of Rhoh in major immune cell subsets identified in MC38 tumors. Neutrophils are shown in black box (□). T...
Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regul...
<p>Analysis by flow cytometry of thymocytes and splenocytes from RhoH<sup>+/+</sup>RhoH<sup>Tg</sup>...
<p>The mRNA expression of the Rho GTPases is depicted as the average 2<sup>−ΔΔCt</sup> value per Rho...
(A) Neutrophils purified from bone marrow of WT and Rhoh-/- mice were incubated with GM-CSF for the ...
(A) Coomassie blue staining of HA pulldown proteins in HoxB8 neutrophils after stimulation with the ...
(A) Representative images of neutrophils from HD and CF patients (n = 4). (B) RHOH expression in neu...
<p>(A) Analysis of RhoH protein expression by western blot in RhoH<sup>-/-</sup>, RhoH<sup>-/-</sup>...
(A) Representative microscopic images of neutrophils freshly isolated from WT and Rhoh-/- mice. (B) ...
Background: RhoH is a constitutively active member of the family of Rho GTPases. Its expression is r...
In contrast to molecular changes associated with increased inflammatory responses, little is known a...
<p>(A) Expression pattern of RhoC and RhoV in the monocyte-lineage. The expression of RhoC and RhoV ...
(A) The mRNA expression of Rhoh in neutrophils expressing WT or mutated HA-RhoH or the corresponding...
Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regul...
(A) Enriched granules and mitochondria from mature HoxB8 neutrophils expressing HA-RhoH or the corre...
Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regul...
Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regul...
<p>Analysis by flow cytometry of thymocytes and splenocytes from RhoH<sup>+/+</sup>RhoH<sup>Tg</sup>...
<p>The mRNA expression of the Rho GTPases is depicted as the average 2<sup>−ΔΔCt</sup> value per Rho...
(A) Neutrophils purified from bone marrow of WT and Rhoh-/- mice were incubated with GM-CSF for the ...
(A) Coomassie blue staining of HA pulldown proteins in HoxB8 neutrophils after stimulation with the ...
(A) Representative images of neutrophils from HD and CF patients (n = 4). (B) RHOH expression in neu...
<p>(A) Analysis of RhoH protein expression by western blot in RhoH<sup>-/-</sup>, RhoH<sup>-/-</sup>...
(A) Representative microscopic images of neutrophils freshly isolated from WT and Rhoh-/- mice. (B) ...
Background: RhoH is a constitutively active member of the family of Rho GTPases. Its expression is r...
In contrast to molecular changes associated with increased inflammatory responses, little is known a...
<p>(A) Expression pattern of RhoC and RhoV in the monocyte-lineage. The expression of RhoC and RhoV ...
(A) The mRNA expression of Rhoh in neutrophils expressing WT or mutated HA-RhoH or the corresponding...
Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regul...
(A) Enriched granules and mitochondria from mature HoxB8 neutrophils expressing HA-RhoH or the corre...
Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regul...
Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regul...
<p>Analysis by flow cytometry of thymocytes and splenocytes from RhoH<sup>+/+</sup>RhoH<sup>Tg</sup>...
<p>The mRNA expression of the Rho GTPases is depicted as the average 2<sup>−ΔΔCt</sup> value per Rho...