PARTICULATE BONE MATRIX USAGE FOR ALVEOLAR BONE CONSERVATION. A HISTOMORPHOMETRIC STUDY.

Different filling materials have been used in an attempt to repair bone loss situations.Objective: The present study aimed to examine the effect of a bone matrix in post-extractionremodelling of the alveolar bone, and to perform a histomorphometric analysis of theresidual alveolar ridges in Wistar rats.Material and Methods: Both rat first lower molars were extracted and the right alveoliwere filled with particles of a bone matrix with mineral components (MO-UNC) (experimentalgroup, EG). The left alveoli were used as a control group (CG). The animals weresacrificed at 0 hrs, 15, 30 and 60 days after extraction, and the samples were processed.Histological sections were made at the level of the mesial alveolus of the first lower molar.Repair of the alveoli was histologically evaluated and a histomorphometric study of totalalveolar volume (TAV), height of the buccal plate (Bh), height of the lingual plate (Lh)and percentage of osseointegration (OI) of the particles was performed to compare theresidual ridges of CG with those of the EG. Statistical analysis of the data was performed.Results: In the cases of the experimental group, newly-formed bone tissue was identifiedaround the MO-UNC particles (osseointegration). Histomorphometric data indicatethat, at 60 days post-extraction, TAV was significantly greater for EG when comparedwith CG (p<0.05) and the percentage of osseointegration of the particles increased as afunction of time (57.6 %, 90.5% y 95.5%, for EG at 15, 30 y 60 days respectively).Conclusions: The bone matrix (MO-UNC) evaluated in this study is an osteoconductivematerial that prevents the collapse of post-extraction alveolar bone.http://www.revista.fcm.unc.edu.ar/2013.70.3/Art.originales/uso.de.matriz.osea/uso.de.matriz.osea.htmpublishedVersionOtras Ciencias de la Salu