Add to ORKGInsulin, a metabolic hormone involved in glucose metabolism, plays also a neuroprotective role in the central nervous system being able to revert the cytotoxic processes induced by Aβ42,a peptide involved in Alzheimer's disease. To reach the brain insulin have to across the BBB therefore an additional delivery strategy results to be necessary. For these aim we performed an insulin conjugated nanogels (NGs-In). Nanogels (NGs) have a great potential in the development of “smart” nanocarriers for (bio)molecular drugs and contrast agent for bioimaging. They are formed by physically or chemically crosslinked polymer networks, characterized by a large and flexible surface available for multivalent bioconjugations. NGs can be produced with hi...
Nanogels (NGs) are nanosized three-dimensional networks of crosslinked hydrophilic polymers. Their t...
Nanogels (NGs) are physically or chemically crosslinked polymer networks and are promising candidat...
Ce travail de thèse s'inscrit dans un domaine de recherche actuellement en pleine expansion, celui d...
Insulin, a metabolic hormone involved in glucose metabolism, plays also a neuroprotective role in th...
Nanogels (NGs) have a great potential in the development of “smart” nanocarriers for (bio)molecular ...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved i...
A growing body of evidence shows the protective role of insulin in Alzheimer's disease (AD). A nanog...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved i...
Nanogels are nanoscalar polymeric networks, characterized by a dynamic internal structure and a flex...
Recent evidences suggest that insulin delivery to the brain can be an important pharmacological ther...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signalling are involved ...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved i...
A kind of glucose-sensitive polypeptide nanogel was prepared via a two-step procedure. First, methox...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved ...
From their first appearance in 1969, when Schnagel and Borwardt reported the radiochemical synthesis...
Nanogels (NGs) are nanosized three-dimensional networks of crosslinked hydrophilic polymers. Their t...
Nanogels (NGs) are physically or chemically crosslinked polymer networks and are promising candidat...
Ce travail de thèse s'inscrit dans un domaine de recherche actuellement en pleine expansion, celui d...
Insulin, a metabolic hormone involved in glucose metabolism, plays also a neuroprotective role in th...
Nanogels (NGs) have a great potential in the development of “smart” nanocarriers for (bio)molecular ...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved i...
A growing body of evidence shows the protective role of insulin in Alzheimer's disease (AD). A nanog...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved i...
Nanogels are nanoscalar polymeric networks, characterized by a dynamic internal structure and a flex...
Recent evidences suggest that insulin delivery to the brain can be an important pharmacological ther...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signalling are involved ...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved i...
A kind of glucose-sensitive polypeptide nanogel was prepared via a two-step procedure. First, methox...
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved ...
From their first appearance in 1969, when Schnagel and Borwardt reported the radiochemical synthesis...
Nanogels (NGs) are nanosized three-dimensional networks of crosslinked hydrophilic polymers. Their t...
Nanogels (NGs) are physically or chemically crosslinked polymer networks and are promising candidat...
Ce travail de thèse s'inscrit dans un domaine de recherche actuellement en pleine expansion, celui d...