Add to ORKGIn this work, a novel mock circulatory loop (MCL) is presented that is capable of simulating both healthy cardiac function and Heart Failure with preserved Ejection Fraction (HFpEF). This MCL differs from others presented in the literature as it features two independently actuated heart chambers, representing the left atrium and the left ventricle. This is an important improvement over other designs as it allows for potential HFpEF treatments to be examined, not just in relation to their effect on the left ventricle but also on the left atrium. The aim of this work was to show that novel MCL designs could be developed to allow for testing of new mechanical circulatory support devices for the treatment of HFpEF. Two loop configurations are p...
Prior to in vivo testing of a left ventricular assist device (LVAD) it is necessary to test it in a ...
A novel in vitro mock circulatory system, which enables to reproduce an inflow restriction, simulati...
Introduction: Mock circulatory loops (MCLs) are mechanical representations of the cardiovascular sys...
In this work, a novel mock circulatory loop (MCL) is presented that is capable of simulating both he...
In the development of a left ventricular assist device (LVAD), it is important to evaluate the LVAD'...
A mock circulatory loop was constructed to facilitate total artificial heart development. The loop i...
Heart disease is attributed as the highest cause of death in the world. Although this could be alle...
In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a necessar...
Mock circulation loops (MCLs) are used to evaluate cardiovascular devices prior to in-vivo trials; h...
Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to anima...
Advances in direct mechanical ventricular actuation devices have been limited by the inability to te...
Integration of biological samples into in vitro mock loops is fundamental to simulate real device's ...
Congestive heart failure is a condition where insufficient blood is circulated around the body resul...
Comprehensive testing and evaluation of cardiovascular device function and performance is required p...
As the number of patients experiencing severe heart failure increases, so too does the need and use ...
Prior to in vivo testing of a left ventricular assist device (LVAD) it is necessary to test it in a ...
A novel in vitro mock circulatory system, which enables to reproduce an inflow restriction, simulati...
Introduction: Mock circulatory loops (MCLs) are mechanical representations of the cardiovascular sys...
In this work, a novel mock circulatory loop (MCL) is presented that is capable of simulating both he...
In the development of a left ventricular assist device (LVAD), it is important to evaluate the LVAD'...
A mock circulatory loop was constructed to facilitate total artificial heart development. The loop i...
Heart disease is attributed as the highest cause of death in the world. Although this could be alle...
In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a necessar...
Mock circulation loops (MCLs) are used to evaluate cardiovascular devices prior to in-vivo trials; h...
Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to anima...
Advances in direct mechanical ventricular actuation devices have been limited by the inability to te...
Integration of biological samples into in vitro mock loops is fundamental to simulate real device's ...
Congestive heart failure is a condition where insufficient blood is circulated around the body resul...
Comprehensive testing and evaluation of cardiovascular device function and performance is required p...
As the number of patients experiencing severe heart failure increases, so too does the need and use ...
Prior to in vivo testing of a left ventricular assist device (LVAD) it is necessary to test it in a ...
A novel in vitro mock circulatory system, which enables to reproduce an inflow restriction, simulati...
Introduction: Mock circulatory loops (MCLs) are mechanical representations of the cardiovascular sys...