Pathway analysis of tonsil follicular B cells and cord blood transitional B cells.

Jourdan K. P. McMillan (13531534)
Patrick O’Donnell (3557501)
Sandra P. Chang (13531537)

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Publication date

August 2022

DOI

10.1371/journal.pone.0273810.g007

Publisher

Public Library of Science (PLoS)

Abstract

Heatmap display of follicular B cells (black band) and transitional B cells (yellow band) from three individual samples for each cell type. Pathways analyzed were (A) IL-6 signaling, NF-kB signaling, PKA signaling; (B) BCR signaling, Cyclins & Cell Cycle Regulation, Th1/Th2 activation; (C) IL-4 signaling, Notch signaling, PI3K signaling in B lymphocytes. Specific genes of interest are boxed in red. Heat map keys are provided on the right of each figure.</p