Supplemental Figures.docx

Supplemental Figure 1. The mRNA expressions of inflammatory factors, including IL6 (A), tnfa (B), ccl2 (C), and ifng (D), in mouse aortic tissues, were determined using the qRT-PCR. gapdh was used as the internal control. Relative gene expression was calculated using the 2-△△Ct method (**P (E) Immunohistochemistry of the mouse aortic tissues using anti-CD31 and anti-MMP9. (F) Immunohistochemistry of the mouse aortic tissues using anti-CD68 (Brown-Forsythe and Welch ANOVA test with Games-Howell’s post-hoc test). Supplemental Figure 2. (A) Through the prediction of the m6A binding site using the SRAMP software (http://www.cuilab.cn/sramp/), there is high confidence region in human and mouse rip3 mRNAs. (B) In the 3’UTR region of rip3, there are conserved and classical RRACU sites.