Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) have now connected stress, epigenetic changes, and aging in yeast by showing that mitochondria-derived reactive oxygen species modulate the chromatin binding capacity of the histone demethylase Rph1p at subtelomeres, resulting in lifespan extension
peer reviewedAcross eukaryotic species, mild mitochondrial stress can have beneficial effects on the...
Recent statistics indicate that the human population is ageing rapidly. Healthy, but also diseased, ...
International audienceIt is becoming increasingly evident that aging is controlled by both genetic a...
Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) ...
Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) ...
SummaryReactive oxygen species (ROS) play complex roles in aging, having both damaging effects and s...
Understanding mechanisms of aging and determinants of life span will help to reduce age-related morb...
Aging is a complex, multi-factorial biological process shared by all living organisms. It is manifes...
Across eukaryotic species, mild mitochondrial stress can have beneficial effects on the lifespan of ...
AbstractMitochondria are principal regulators of cellular function and metabolism through production...
A central aspect of aging research concerns the question of when individuality in lifespan arises. H...
Adaptive responses to stress, including hormesis, have been implicated in longevity, but their mecha...
The longevity of an organism depends on the health of its cells. Throughout life cells are exposed t...
Organisms respond to mitochondrial stress through the upregulation of an array of protective genes, ...
Oxidative stress constitutes the basis of physio-pathological situations such as neurodegenerative d...
peer reviewedAcross eukaryotic species, mild mitochondrial stress can have beneficial effects on the...
Recent statistics indicate that the human population is ageing rapidly. Healthy, but also diseased, ...
International audienceIt is becoming increasingly evident that aging is controlled by both genetic a...
Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) ...
Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) ...
SummaryReactive oxygen species (ROS) play complex roles in aging, having both damaging effects and s...
Understanding mechanisms of aging and determinants of life span will help to reduce age-related morb...
Aging is a complex, multi-factorial biological process shared by all living organisms. It is manifes...
Across eukaryotic species, mild mitochondrial stress can have beneficial effects on the lifespan of ...
AbstractMitochondria are principal regulators of cellular function and metabolism through production...
A central aspect of aging research concerns the question of when individuality in lifespan arises. H...
Adaptive responses to stress, including hormesis, have been implicated in longevity, but their mecha...
The longevity of an organism depends on the health of its cells. Throughout life cells are exposed t...
Organisms respond to mitochondrial stress through the upregulation of an array of protective genes, ...
Oxidative stress constitutes the basis of physio-pathological situations such as neurodegenerative d...
peer reviewedAcross eukaryotic species, mild mitochondrial stress can have beneficial effects on the...
Recent statistics indicate that the human population is ageing rapidly. Healthy, but also diseased, ...
International audienceIt is becoming increasingly evident that aging is controlled by both genetic a...
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