Towards a better assessment of the mercury-selenium antagonism in fish

The fish were killed by cutting the spinal cord in t 0 t 1 t 2 and t 3 All the data related to the fish growth were recorded similar growth was observed for all exposure conditions. The levels of Hg T and Se T in the fish diet were also measured by ICP MS. Hg T in control and MeHg spiked diets were 0.05 ±0.002 and 0.24 ±0.01 mg/kg, respectively, whereas Se T were 0.95 ±0.02 mg/kg and 5.41 ±0.36 mg/kg in the control and the spiked diets. Se saturation ( p = 0.30) occurs after two months of fish be exposed throught diet to SeMet solely. Quasilinear (R 2 0.99) bioaccumulation of Hg in the fish exposed individualy to MeHg during 3 months. Threshold (p = 0.30) in total Hg level is reached in fish exposed simultaneously to MeHg and SeMet. ↓ of Hg burden 18%) after two months of fish exposure to SeMet and no MeHg. Possible Hg detoxification due to Se supplementation.FCT, MERSEL-FISH - 2018DAN1568N/