Add to ORKG[[abstract]]The aim of this study was to investigate the involvement of androgen, mainly testosterone, in the expression of renal senescence marker protein-30 (SMP30) in male rats. We found that the renal SMP30 expression was up-regulated by endogenous testosterone stimulation during puberty. Interestingly, androgen-deficient orchidectomized (ORX) rats exhibited lower SMP30 mRNA and protein expression in the kidney, and that was restored by testosterone propionate (TP) replacement. Abrogation of androgen receptor (AR) activity by co-treatment with flutamide abolished testosterone-induced SMP30 expression in the kidney as well as in the NRK52E cells. However, SMP30 expression was unaltered in the liver of ORX rats. We also showed a positive ...
The effect of testosterone replacement in middle-aged rats on renal function and apoptosis of mesang...
Abstract Background The morbidity of nephrolithiasis is 2–3 times higher in males than in females, s...
Calcium and phosphate are vital for the organism and constitute essential components of the skeleton...
[[abstract]]The aim of this study was to investigate the involvement of androgen, mainly testosteron...
Renal angiotensinogen (ang-n) mRNA concentration in the male WKY rat increases significantly during ...
Although gender differences in the renal handling of calcium have been reported, the overall contrib...
Although gender differences in the renal handling of calcium have been reported, the overall contrib...
Testosterone promotes apoptotic damage in human renal tubular cells.BackgroundApoptosis is a mode of...
Background. Apoptosis is a mode of cell death that participates in the kidney physiologic remodeling...
We have studied the extent to which mouse renal cytochrome P-450 isoenzymes are sexually differentia...
BACKGROUND: Androgen-dependent proteins (lipocalins) circulate in blood of male rats and mice and, b...
BACKGROUND: Androgen-dependent proteins (lipocalins) circulate in blood of male rats and mice and, b...
Objective: the bladder can be considered a target organ for testosterone action, and low testosteron...
The influences of sex hormones on the blood pressure regulation have been known since decades. These...
We have previously shown that sexual dimorphism in the expression of mouse renal cytochrome P450s is...
The effect of testosterone replacement in middle-aged rats on renal function and apoptosis of mesang...
Abstract Background The morbidity of nephrolithiasis is 2–3 times higher in males than in females, s...
Calcium and phosphate are vital for the organism and constitute essential components of the skeleton...
[[abstract]]The aim of this study was to investigate the involvement of androgen, mainly testosteron...
Renal angiotensinogen (ang-n) mRNA concentration in the male WKY rat increases significantly during ...
Although gender differences in the renal handling of calcium have been reported, the overall contrib...
Although gender differences in the renal handling of calcium have been reported, the overall contrib...
Testosterone promotes apoptotic damage in human renal tubular cells.BackgroundApoptosis is a mode of...
Background. Apoptosis is a mode of cell death that participates in the kidney physiologic remodeling...
We have studied the extent to which mouse renal cytochrome P-450 isoenzymes are sexually differentia...
BACKGROUND: Androgen-dependent proteins (lipocalins) circulate in blood of male rats and mice and, b...
BACKGROUND: Androgen-dependent proteins (lipocalins) circulate in blood of male rats and mice and, b...
Objective: the bladder can be considered a target organ for testosterone action, and low testosteron...
The influences of sex hormones on the blood pressure regulation have been known since decades. These...
We have previously shown that sexual dimorphism in the expression of mouse renal cytochrome P450s is...
The effect of testosterone replacement in middle-aged rats on renal function and apoptosis of mesang...
Abstract Background The morbidity of nephrolithiasis is 2–3 times higher in males than in females, s...
Calcium and phosphate are vital for the organism and constitute essential components of the skeleton...