Antimicrobial-resistant (AMR) microorganisms are an increasingly seriousproblem worldwide, accounting for thousands of fatalities annually. The current literature on combating AMR pathogens often centers on commensal microbes such as Lactobacillus species, which are most frequently found in asymptomatic ‘healthy’ patients and are believed to elicit protective effects. In this dissertation, I sought to investigate the protective effect of Lactobacillus crispatus, utilizing our vast collection of clinical isolates. Previous work from our lab had found that cell-free-supernatant (CFS) of L. crispatus is robustly bactericidal, and that this killing activity does not depend on hydrogen peroxide or lactic acid. We identified phenyl-lactic acid (P...
As many as 1 in 2 women will have at least one urinary tract infection (UTI) in their lifetime. UTIs...
National audienceProbiotics are defined by the World Health Organization as live microorga...
Background: Vaginal lactic acid bacteria defend the host against pathogens through a combination of ...
Probiotics such as various strains of Lactobacillaceae have been shown to have antimicrobial and imm...
Bacteriocins are the most important natural preservatives against pathogens, but their limited spect...
Lactic acid bacteria were reported as a promising alternative to antibiotics against pathogens. Amon...
Introduction: Bacteriocins produced by lactic acid bacteria (LAB) have the potential to cover a very...
Background: Pseudomonas aeruginosa, as an important opportunistic pathogen, can produce P. aeruginos...
Multidrug-resistant (MDR) bacterial infections are a top five global public health threat, causing 2...
Lactobacillus is a genus of lactic acid bacteria frequently used as healthpromoting probiotics. Usin...
Abstract Background and Objective: Probiotics are living microorganisms that have beneficial ...
Background: This study aims to investigate the antimicrobial ability and mechanism analysis of Lacto...
Lactic acid bacteria (LAB) are probiotic candidates that may restore the balance of microbiota popul...
Lactococcin B (LcnB) is a small, hydrophobic, positively charged bacteriocin produced by Lactococcus...
The ever increasing multidrug-resistance of clinically important pathogens and the lack of novel ant...
As many as 1 in 2 women will have at least one urinary tract infection (UTI) in their lifetime. UTIs...
National audienceProbiotics are defined by the World Health Organization as live microorga...
Background: Vaginal lactic acid bacteria defend the host against pathogens through a combination of ...
Probiotics such as various strains of Lactobacillaceae have been shown to have antimicrobial and imm...
Bacteriocins are the most important natural preservatives against pathogens, but their limited spect...
Lactic acid bacteria were reported as a promising alternative to antibiotics against pathogens. Amon...
Introduction: Bacteriocins produced by lactic acid bacteria (LAB) have the potential to cover a very...
Background: Pseudomonas aeruginosa, as an important opportunistic pathogen, can produce P. aeruginos...
Multidrug-resistant (MDR) bacterial infections are a top five global public health threat, causing 2...
Lactobacillus is a genus of lactic acid bacteria frequently used as healthpromoting probiotics. Usin...
Abstract Background and Objective: Probiotics are living microorganisms that have beneficial ...
Background: This study aims to investigate the antimicrobial ability and mechanism analysis of Lacto...
Lactic acid bacteria (LAB) are probiotic candidates that may restore the balance of microbiota popul...
Lactococcin B (LcnB) is a small, hydrophobic, positively charged bacteriocin produced by Lactococcus...
The ever increasing multidrug-resistance of clinically important pathogens and the lack of novel ant...
As many as 1 in 2 women will have at least one urinary tract infection (UTI) in their lifetime. UTIs...
National audienceProbiotics are defined by the World Health Organization as live microorga...
Background: Vaginal lactic acid bacteria defend the host against pathogens through a combination of ...