Estimation of COVID-19 vaccine effectiveness against hospitalisation in individuals aged ≥ 65 years using electronic health registries; a pilot study in four EU/EEA countries, October 2021 to March 2022.
- Sentís, Alexis
- Kislaya, Irina
- Nicolay, Nathalie
- Meijerink, Hinta
- Starrfelt, Jostein
- Martínez-Baz, Iván
- Castilla, Jesús
- Nielsen, Katrine Finderup
- Hansen, Christian Holm
- Emborg, Hanne-Dorthe
- Nardone, Anthony
- Derrough, Tarik
- Valenciano, Marta
- Nunes, Baltazar
- Monge, Susana
- VEBIS-Lot4 working group
Publication date
July 2022
DOI Publisher
European Centre for Disease Control and Prevention (ECDC)Abstract
By employing a common protocol and data from electronic health registries in Denmark, Navarre (Spain), Norway and Portugal, we estimated vaccine effectiveness (VE) against hospitalisation due to COVID-19 in individuals aged ≥ 65 years old, without previous documented infection, between October 2021 and March 2022. VE was higher in 65-79-year-olds compared with ≥ 80-year-olds and in those who received a booster compared with those who were primary vaccinated. VE remained high (ca 80%) between ≥ 12 and < 24 weeks after the first booster administration, and after Omicron became dominant
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