International audienceObjective: Quantification of brain injury in patients with variable disability despite similar disease duration may be relevant to identify the mechanisms underlying disability in MS. We aimed to compare grey-matter sodium abnormalities (GMSA), a parameter reflecting neuronal and astrocyte dysfunction, in MS patients with benign MS (BMS) and non-benign MS (NBMS). Methods: We identified never-treated BMS patients in our local MS database of 1352 patients. A group with NBMS was identified with same disease duration. All participants underwent 23 Na MRI. The existence of GMSA was detected by statistical analysis. Results: In total, 102 individuals were included (21 BMS, 25 NBMS and 56 controls). GMSA was detected in 10 BM...
Purpose: In secondary progressive Multiple Sclerosis (SPMS), global neurodegeneration as a driver of...
BACKGROUND: In multiple sclerosis, grey matter (GM) damage appears more clinically relevant than eit...
Brain regions responsible for cognitive dysfunction in MS and neuromyelitis optica spectrum disorder...
International audienceObjective: Quantification of brain injury in patients with variable disability...
OBJECTIVE: Sodium (23Na)-MRI is an emerging imaging technique to investigate in vivo changes in tiss...
International audienceOBJECTIVE: To investigate whether brain total sodium accumulation assessed by ...
Objective Sodium (23 Na)-MRI is an emerging imaging technique to investigate in vivo changes in tiss...
Zaaraoui, Wafaa Konstandin, Simon Audoin, Bertrand Nagel, Armin M Rico, Audrey Malikova, Irina Souli...
Introduction: The source of Tissue Sodium Concentration (TSC) increase in Multiple Sclerosis (MS) re...
Intra-axonal accumulation of sodium ions is one of the key mechanisms of delayed neuro-axonal degene...
Background: Multiple sclerosis (MS) is characterized by demyelinating and degenerative processes wit...
OBJECTIVE: To determine the relation of gray matter (GM) and white matter (WM) brain volumes, and WM...
Intra-axonal accumulation of sodium ions is one of the key mechanisms of delayed neuro-axonal degene...
Intra-axonal accumulation of sodium ions is one of the key mechanisms of delayed neuro-axonal degene...
Intra-axonal accumulation of sodium ions is one of the key mechanisms of delayed neuro-axonal degene...
Purpose: In secondary progressive Multiple Sclerosis (SPMS), global neurodegeneration as a driver of...
BACKGROUND: In multiple sclerosis, grey matter (GM) damage appears more clinically relevant than eit...
Brain regions responsible for cognitive dysfunction in MS and neuromyelitis optica spectrum disorder...
International audienceObjective: Quantification of brain injury in patients with variable disability...
OBJECTIVE: Sodium (23Na)-MRI is an emerging imaging technique to investigate in vivo changes in tiss...
International audienceOBJECTIVE: To investigate whether brain total sodium accumulation assessed by ...
Objective Sodium (23 Na)-MRI is an emerging imaging technique to investigate in vivo changes in tiss...
Zaaraoui, Wafaa Konstandin, Simon Audoin, Bertrand Nagel, Armin M Rico, Audrey Malikova, Irina Souli...
Introduction: The source of Tissue Sodium Concentration (TSC) increase in Multiple Sclerosis (MS) re...
Intra-axonal accumulation of sodium ions is one of the key mechanisms of delayed neuro-axonal degene...
Background: Multiple sclerosis (MS) is characterized by demyelinating and degenerative processes wit...
OBJECTIVE: To determine the relation of gray matter (GM) and white matter (WM) brain volumes, and WM...
Intra-axonal accumulation of sodium ions is one of the key mechanisms of delayed neuro-axonal degene...
Intra-axonal accumulation of sodium ions is one of the key mechanisms of delayed neuro-axonal degene...
Intra-axonal accumulation of sodium ions is one of the key mechanisms of delayed neuro-axonal degene...
Purpose: In secondary progressive Multiple Sclerosis (SPMS), global neurodegeneration as a driver of...
BACKGROUND: In multiple sclerosis, grey matter (GM) damage appears more clinically relevant than eit...
Brain regions responsible for cognitive dysfunction in MS and neuromyelitis optica spectrum disorder...