International audienceWe investigate the relationship between the long-term (Quaternary) interplate coupling and the short-term geodetically derived interseismic coupling at the Central Ecuador subduction zone. At this nonaccretionary margin, the Cabo Pasado shelf promontory and coastal area are associated with two inter-plate geodetically locked patches. The deepest patch ruptured co-seismically during the Mw7.8-2016 Pedernales earthquake, while the shallowest underwent dominantly after-slip. Marine geophysical and chronostratigraphic data allow reconstructing the Quaternary tectonic evolution of the shelf promontory and substantiating variation of the long-term inter-plate coupling that led to the geodetically locked patches. Prior to ∼1....