Several studies suggest that human longevity appears to be linked inextricably with optimal functioning of the immune system, suggesting that specific genetic determinants may reside in loci that regulate the immune response, as human leukocyte antigen (HLA) and killer cell immunoglobulin-like receptor (KIR) genes. It has been suggested that longevity is associated with positive selection of alleles (i.e., HLA-DR11) or haplotypes (i.e., HLAB8, DR3) that confer resistance to infectious disease(s). On the other hand, the cytolytic activity of natural killer (NK) cells is controlled by activating and inhibitory cell-surface receptors, including KIR. The genetic diversity of the KIR loci with respect to successful aging has been analyzed ...
The killer cell immunoglobulin-like receptor (KIR)-human leukocyte antigen (HLA) interaction represe...
Killer cell immunoglobulin-like receptors (KIR) gene frequencies vary between populations and contri...
Ageing is a process characterised by progressive loss of function in multiple different organ system...
Several studies suggest that human longevity appears to be linked inextricably with optimal function...
Human leukocyte antigen (HLA) alleles, regulating type and intensity of the immune response, might i...
Some genetic determinants of longevity might reside in those polymorphisms for the immune system gen...
Some genetic determinants of longevity might reside in those polymorphisms for the immune system gen...
\u2018Immunogenetics of Aging\u2019 is a component that was first included in the 14th International...
The demographic and social changes of the past decades have determined improvements in public health...
The aim of this study was to analyse the role of GM allotypes, i.e. the hereditary antigenic determi...
'Immunogenetics of Aging' is a component that was first included in the 14th International HLA and I...
'Immunogenetics of Aging' is a component that was first included in the 14th International HLA and I...
Background and aims: Human longevity seems to be directly correlated with optimal functioning of the...
Killer immunoglobulin-like receptors (KIRs) regulate the activation of natural killer cells through...
The killer cell immunoglobulin-like receptor (KIR)-human leukocyte antigen (HLA) interaction represe...
Killer cell immunoglobulin-like receptors (KIR) gene frequencies vary between populations and contri...
Ageing is a process characterised by progressive loss of function in multiple different organ system...
Several studies suggest that human longevity appears to be linked inextricably with optimal function...
Human leukocyte antigen (HLA) alleles, regulating type and intensity of the immune response, might i...
Some genetic determinants of longevity might reside in those polymorphisms for the immune system gen...
Some genetic determinants of longevity might reside in those polymorphisms for the immune system gen...
\u2018Immunogenetics of Aging\u2019 is a component that was first included in the 14th International...
The demographic and social changes of the past decades have determined improvements in public health...
The aim of this study was to analyse the role of GM allotypes, i.e. the hereditary antigenic determi...
'Immunogenetics of Aging' is a component that was first included in the 14th International HLA and I...
'Immunogenetics of Aging' is a component that was first included in the 14th International HLA and I...
Background and aims: Human longevity seems to be directly correlated with optimal functioning of the...
Killer immunoglobulin-like receptors (KIRs) regulate the activation of natural killer cells through...
The killer cell immunoglobulin-like receptor (KIR)-human leukocyte antigen (HLA) interaction represe...
Killer cell immunoglobulin-like receptors (KIR) gene frequencies vary between populations and contri...
Ageing is a process characterised by progressive loss of function in multiple different organ system...