Add to ORKGThe work described here complements previous findings on monepantel (MNP) pharmacological behaviour in cattle. MNP was given alone or co-administered with macrocyclic lactones or benzimidazoles to calves naturally infected with gastrointestinal nematodes (GIN) resistant to ivermectin (IVM) in two commercial cattle farms. Both pharmacokinetic and efficacy assessments were performed. In Farm A, two groups (n= 15) of male calves were treated with either MNP orally (2.5 mg/kg) or IVM subcutaneously (sc, 0.2 mg/kg). In Farm B, eight groups (n=15) of male calves were treated with MNP, IVM, abamectin (ABA, oral, 0.2 mg/kg), ricobendazole (RBZ, sc, 3.75 mg/kg), albendazole (ABZ, oral, 5 mg/kg), MNP+ABA, MNP+RBZ and MNP+ABZ (all at the mentioned dos...
The maintenance of anthelmintic-susceptible parasite refugia to delay the onset of anthelmintic resi...
Monepantel (MNP) is a novel anthelmintic compound launched into the veterinary pharmaceutical market...
In an attempt to manage anthelmintic resistance, nematodicidal drug combinations could be considered...
The increasing levels of resistance to all traditional anthelmintic classes have encouraged the sear...
The current work assessed the relationship between pharmacokinetic behavior andclinical efficacy of ...
The goals of the current study were to evaluate the potential pharmacokinetic (PK) interactions and ...
In a context of nematodicidal resistance, anthelmintic combinations have emerged as a reliable pharm...
Combination of anthelmintics with different mechanisms of action has been suggested as an effective ...
The goal of the current study was to evaluate, the impact of anthelmintic resistance (AR) on the pro...
Aims: The main goal of the current study was to evaluate, on a commercial beef cattle farm, the impa...
The current work assessed the relationship between pharmacokinetic behavior and clinical efficacy of...
Monepantel (MNP) is a novel anthelmintic drug with a distinctive mode of action. MNP is active again...
Nematodicidal combinations have been proposed as a valid strategy to achieve effective nematode cont...
The concurrent administration of drugs is currently used in veterinary medicine. In cattle, the coad...
The current study evaluated the efficacy and the potential pharmacokinetic(PK) interactions occurrin...
The maintenance of anthelmintic-susceptible parasite refugia to delay the onset of anthelmintic resi...
Monepantel (MNP) is a novel anthelmintic compound launched into the veterinary pharmaceutical market...
In an attempt to manage anthelmintic resistance, nematodicidal drug combinations could be considered...
The increasing levels of resistance to all traditional anthelmintic classes have encouraged the sear...
The current work assessed the relationship between pharmacokinetic behavior andclinical efficacy of ...
The goals of the current study were to evaluate the potential pharmacokinetic (PK) interactions and ...
In a context of nematodicidal resistance, anthelmintic combinations have emerged as a reliable pharm...
Combination of anthelmintics with different mechanisms of action has been suggested as an effective ...
The goal of the current study was to evaluate, the impact of anthelmintic resistance (AR) on the pro...
Aims: The main goal of the current study was to evaluate, on a commercial beef cattle farm, the impa...
The current work assessed the relationship between pharmacokinetic behavior and clinical efficacy of...
Monepantel (MNP) is a novel anthelmintic drug with a distinctive mode of action. MNP is active again...
Nematodicidal combinations have been proposed as a valid strategy to achieve effective nematode cont...
The concurrent administration of drugs is currently used in veterinary medicine. In cattle, the coad...
The current study evaluated the efficacy and the potential pharmacokinetic(PK) interactions occurrin...
The maintenance of anthelmintic-susceptible parasite refugia to delay the onset of anthelmintic resi...
Monepantel (MNP) is a novel anthelmintic compound launched into the veterinary pharmaceutical market...
In an attempt to manage anthelmintic resistance, nematodicidal drug combinations could be considered...