A review of substrates for solid-state fermentation of Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (Agaricomycetes) for Basidiome production

Mushrooms in the genus Ganoderma have been collected and used as medicine since ancient times. However, commercial basidiome production has only recently been achieved. The solid substrates for basidiome production usually consist of lignocellulosic materials as the major component and the supplements (e.g., different types of bran and flour) as the minor segment. Research on substrates for solid-state fermentation with the purpose of basidiome production has focused on investigating locally available agrowaste materials, and their suitability is judged by the economic outputs. This review summarizes the formulations of the substrates and discusses their effects on the yield of basidiome or its bioactive compounds. Through a comprehensive look, this review concludes that future research focused on various treatments to modulate extracellular enzyme production may bring more options to the table for innovative solid substrate formulation.Fil: Amiri-Sadeghan, Amir. Tabriz University; IránFil: Aftabi, Younes. Tabriz University; IránFil: Ramezanzadeh Arvanaghi, Habib. Tabriz University; IránFil: Shokri, Ehsan. Agricultural Biotechnology Research Institute of Iran; IránFil: Khalili, Majid. Tabriz University; IránFil: Seyedrezazadeh, Ensiyeh. Tabriz University; IránFil: Kuhar, José Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentin