Selective extraction of antimicrobial agents from Jodina rhombifolia by supercritical fluid carbon dioxide: Phytochemical profile
- Marín, Edith Magdalena
- Reyes, María Gimena
- Audisio, Marcela Carina
- Zacur, José L.
- Uriburu, María L.
- Nicotra, Viviana Estela
DOIAbstract
The goals of this study were to determine the phytochemical profile of Jodina rhombifolia and to evaluate the ability of supercritical fluids (ScFCO2) to selectively extract the metabolites responsible for the bioactivity. This species has simple aromatic compounds and lignan monomers, as well as glycerides containing epoxidized saturated fatty acids. Regarding the extraction by ScFCO2, the extracts showed a higher antimicrobial activity against human pathogenic strains, with respect to the ethanolic extracts obtained from plant residues after extraction by ScFCO2. Furthermore, the bioactive compounds were concentrated in just 1% P/P of the weight of the dry plant material. Extraction by ScFCO2 was carried out under different conditions of ...
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