: The phenotypic identification of different NK cell subsets allows more in-depth characterization of KIR repertoire and function, which are of potential interest in KIR and disease association studies. KIR genes are highly polymorphic, but a great homology exists among the various sequences and few monoclonal antibodies (mAbs) specifically recognize a single KIR. This is the case of HP-DM1 which was demonstrated by analysis of cell transfectants and epitope mapping to be exclusively KIR2DL1-specific, covering all allotypes identified to date, except for KIR2DL1*022 and *020, and also to react with KIR2DS1*013. Here, we compared in immunofluorescence analyses the staining of HP-DM1 with other available mAbs to precisely identify KIR2DL1+ NK...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
The phenotypic identification of different NK cell subsets allows more in-depth characterization of ...
The phenotypic identification of different NK cell subsets allows more in-depth characterization of ...
: Killer immunoglobulin-like receptor (KIR) genes code for a family of inhibitory and activating rec...
Killer immunoglobulin-like receptor (KIR) genes code for a family of inhibitory and activating recep...
Cumulative activating and inhibitory receptor signaling controls the functional output of individual...
The killer cell immunoglobulin‐like receptor (KIR) KIR2DS2 induces NK cell activation upon ligation ...
International audienceNatural killer (NK) cells are key components of the innate anti-viral and anti...
International audienceNatural killer (NK) cells are key components of the innate anti-viral and anti...
International audienceNatural killer (NK) cells are key components of the innate anti-viral and anti...
International audienceNatural killer (NK) cells are key components of the innate anti-viral and anti...
Analysis of killer cell immunoglobulin-like receptor (KIR) expression has been notoriously difficult...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
The phenotypic identification of different NK cell subsets allows more in-depth characterization of ...
The phenotypic identification of different NK cell subsets allows more in-depth characterization of ...
: Killer immunoglobulin-like receptor (KIR) genes code for a family of inhibitory and activating rec...
Killer immunoglobulin-like receptor (KIR) genes code for a family of inhibitory and activating recep...
Cumulative activating and inhibitory receptor signaling controls the functional output of individual...
The killer cell immunoglobulin‐like receptor (KIR) KIR2DS2 induces NK cell activation upon ligation ...
International audienceNatural killer (NK) cells are key components of the innate anti-viral and anti...
International audienceNatural killer (NK) cells are key components of the innate anti-viral and anti...
International audienceNatural killer (NK) cells are key components of the innate anti-viral and anti...
International audienceNatural killer (NK) cells are key components of the innate anti-viral and anti...
Analysis of killer cell immunoglobulin-like receptor (KIR) expression has been notoriously difficult...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...
International audienceThe interactions of killer Ig-like receptor 2D (KIR2D) with HLA-C ligands cont...