Growth and CD4 patterns of adolescents living with perinatally acquired HIV worldwide, a CIPHER cohort collaboration analysis
- Jesson J.
- Crichton S.
- Quartagno M.
- Yotebieng M.
- Abrams E. J.
- Chokephaibulkit K.
- Le Coeur S.
- Ake-Assi M. -H.
- Patel K.
- Pinto J.
- Paul M.
- Vreeman R.
- Davies M. -A.
- Ben-Farhat J.
- Van Dyke R.
- Judd A.
- Mofenson L.
- Vicari M.
- Seage G.
- Bekker L. -G.
- Essajee S.
- Gibb D.
- Penazzato M.
- Collins I. J.
- Wools-Kaloustian K.
- Slogrove A.
- Powis K.
- Williams P.
- Matshaba M.
- Thahane L.
- Nyasulu P.
- Lukhele B.
- Mwita L.
- Kekitiinwa-Rukyalekere A.
- Wanless S.
- Goetghebuer T.
- Thorne C.
- Warszawski J.
- Galli L.
- van Rossum A. M. C.
- Giaquinto C.
- Marczynska M.
- Marques L.
- Prata F.
- Ene L.
- Okhonskaya L.
- Navarro M.
- Frick A.
- Naver L.
- Kahlert C.
- Volokha A.
- Chappell E.
- Pape J. W.
- Rouzier V.
- Marcelin A.
- Succi R.
- Sohn A. H.
- Kariminia A.
- Edmonds A.
- Lelo P.
- Lyamuya R.
- Ogalo E. A.
- Odhiambo F. A.
- Haas A. D.
- Bolton C.
- Muhairwe J.
- Tweya H.
- Sylla M.
- D'Almeida M.
- Renner L.
- Abzug M. J.
- Oleske J.
- Purswani M.
- Teasdale C.
- Nuwagaba-Biribonwoha H.
- Goodall R.
- Leroy V.
DOIAbstract
INTRODUCTION: Adolescents living with HIV are subject to multiple co-morbidities, including growth retardation and immunodeficiency. We describe growth and CD4 evolution during adolescence using data from the Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) global project. METHODS: Data were collected between 1994 and 2015 from 11 CIPHER networks worldwide. Adolescents with perinatally acquired HIV infection (APH) who initiated antiretroviral therapy (ART) before age 10 years, with at least one height or CD4 count measurement while aged 10-17 years, were included. Growth was measured using height-for-age Z-scores (HAZ, stunting if 7 years in sub-Saharan African regions. At age 10, stunting ranged from 6% in North ...
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