Synthesis of novel 7,7-difluoroprostacyclin and 15-deoxy-15,15-difluoro-PGF2? derivatives will be presented. These compounds show high affinity to prostaglandin receptors and potent biological activities
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
In the present study, five derivatives have been designed to be synthesized as possible mutual prodr...
A series of novel derivatives of the nonsteroidal anti-inflammatory drug (NSAID) sulindac sulfide we...
A novel series of prostaglandin analogues with a seven-membered ring scaffold was designed, synthesi...
Prostaglandin and prostacyclin compounds which are fluorine substituted in any one or more of the fo...
PPARs are transcription factors that govern lipid and glucose homeostasis and play a central role in...
A number of new fluorophenyl 4-oxocyclopentane[d]isoxazolines and their dioxolane derivatives has be...
PPARs are transcription factors that govern lipid and glucose homeostasis and play a central role in...
To identify G protein-biased and highly subtype-selective EP2 receptor agonists, a series of bicycli...
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily ...
Identification of the primary products of cyclo-oxygenase (COX)/prostaglandin synthase(s), which occ...
Prostaglandin and prostacyclin compounds which are fluorine substituted in any one or more of the fo...
The synthesis of new fluorinated primary nitrocompounds ?(2-fluorophenyl)and (4-fluorophenyl)-(2-nit...
The many potent biological affects of the prostaglandins make this family of compounds and their str...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
In the present study, five derivatives have been designed to be synthesized as possible mutual prodr...
A series of novel derivatives of the nonsteroidal anti-inflammatory drug (NSAID) sulindac sulfide we...
A novel series of prostaglandin analogues with a seven-membered ring scaffold was designed, synthesi...
Prostaglandin and prostacyclin compounds which are fluorine substituted in any one or more of the fo...
PPARs are transcription factors that govern lipid and glucose homeostasis and play a central role in...
A number of new fluorophenyl 4-oxocyclopentane[d]isoxazolines and their dioxolane derivatives has be...
PPARs are transcription factors that govern lipid and glucose homeostasis and play a central role in...
To identify G protein-biased and highly subtype-selective EP2 receptor agonists, a series of bicycli...
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily ...
Identification of the primary products of cyclo-oxygenase (COX)/prostaglandin synthase(s), which occ...
Prostaglandin and prostacyclin compounds which are fluorine substituted in any one or more of the fo...
The synthesis of new fluorinated primary nitrocompounds ?(2-fluorophenyl)and (4-fluorophenyl)-(2-nit...
The many potent biological affects of the prostaglandins make this family of compounds and their str...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
A series of substituted 1,5-diarylpyrrole-3-alkoxyethyl ethers were previously synthesized and the p...
In the present study, five derivatives have been designed to be synthesized as possible mutual prodr...
A series of novel derivatives of the nonsteroidal anti-inflammatory drug (NSAID) sulindac sulfide we...