A brief overview of the key role for heavy-metal compounds in medicine is given, with a special focus on platinum compounds used in treatment of cancer. Molecular aspects of the mechanism of action are presented in more detail
Classical chemotherapeutics, such as cisplatin and its analogues, have been highly successful in the...
Platinum-complexes represent some of the most successful groups of clinically used anticancer drugs....
Countless expectations converge in the multidisciplinary endeavour for the search and development o...
The discovery of cisplatin (cis-Pt(NH3)2Cl2) as an antineoplastic agent has focused attention on the...
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design of new ...
More than 99% of currently approved clinical drugs are organic compounds. In contrast, the percentag...
Includes abstract.Includes bibliographical references (leaves 139-160).Cisplatin is one of the most ...
A critical discussion is presented about the possible role of Pt-protein interactions in the mechani...
The field of medicinal inorganic chemistry has grown consistently during the past 50 years; however,...
More than 99% of currently approved clinical drugs are organic compounds. In contrast, the percentag...
The field of medicinal inorganic chemistry has grown consistently during the past 50 years; however,...
Since the introduction of cisplatin in cancer therapy, metal complexes and organometallic compounds ...
Cisplatin and other platinum compounds have had a huge impact in the treatment of cancers and are ap...
Classical chemotherapeutics, such as cisplatin and its analogues, have been highly successful in the...
Platinum-complexes represent some of the most successful groups of clinically used anticancer drugs....
Countless expectations converge in the multidisciplinary endeavour for the search and development o...
The discovery of cisplatin (cis-Pt(NH3)2Cl2) as an antineoplastic agent has focused attention on the...
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design of new ...
More than 99% of currently approved clinical drugs are organic compounds. In contrast, the percentag...
Includes abstract.Includes bibliographical references (leaves 139-160).Cisplatin is one of the most ...
A critical discussion is presented about the possible role of Pt-protein interactions in the mechani...
The field of medicinal inorganic chemistry has grown consistently during the past 50 years; however,...
More than 99% of currently approved clinical drugs are organic compounds. In contrast, the percentag...
The field of medicinal inorganic chemistry has grown consistently during the past 50 years; however,...
Since the introduction of cisplatin in cancer therapy, metal complexes and organometallic compounds ...
Cisplatin and other platinum compounds have had a huge impact in the treatment of cancers and are ap...
Classical chemotherapeutics, such as cisplatin and its analogues, have been highly successful in the...
Platinum-complexes represent some of the most successful groups of clinically used anticancer drugs....
Countless expectations converge in the multidisciplinary endeavour for the search and development o...
DOI
Add to ORKG