Plants utilise intracellular nucleotide-binding, leucine-rich repeat (NLR) immune receptors to detect pathogen effectors and activate local and systemic defence. NRG1 and ADR1 “helper” NLRs (RNLs) cooperate with enhanced disease susceptibility 1 (EDS1), senescence-associated gene 101 (SAG101) and phytoalexin-deficient 4 (PAD4) lipase-like proteins to mediate signalling from TIR domain NLR receptors (TNLs). The mechanism of RNL/EDS1 family protein cooperation is not understood. Here, we present genetic and molecular evidence for exclusive EDS1/SAG101/NRG1 and EDS1/PAD4/ADR1 co-functions in TNL immunity. Using immunoprecipitation and mass spectrometry, we show effector recognition-dependent interaction of NRG1 with EDS1 and SAG101, but not PA...
Plants deploy cell-surface and intracellular leucine rich-repeat domain (LRR) immune receptors to de...
Plants use both cell surface and intracellular immune receptors with leucine rich-repeat (LRRs) to d...
Arabidopsis pathogen effector-triggered immunity (ETI) is controlled by a family of three lipase-lik...
Plants utilise intracellular nucleotide-binding, leucine-rich repeat (NLR) immune receptors to detec...
Plants encode intracellular immune receptors that detect pathogen effectors and activate defence mec...
Plant intracellular nucleotide-binding/leucine-rich repeat (NLR) immune receptors are activated by p...
The EDS1 family of structurally unique lipase-like proteins EDS1, SAG101, and PAD4 evolved in seed p...
Heterodimeric complexes incorporating the lipase-like proteins EDS1 with PAD4 or SAG101 are central ...
In both plants and animals, nucleotide-binding leucine-rich repeat (NLR) receptors play crucial role...
Plant nucleotide-binding leucine-rich repeat-containing (NLR) receptors with an N-terminal Toll/ int...
Effector-triggered immunity (ETI) in plants involves a large family of nucleotide-binding leucine-ri...
Heterodimeric complexes incorporating the lipase-like proteins EDS1 with PAD4 or SAG101 are central ...
International audienceHeterodimeric complexes containing the lipase-like protein ENHANCED DISEASE SU...
Plants use a complex receptor-based immune system to resist pathogen attacks. Intracellular NUCLEOTI...
Plant pathogen-activated immune signaling by nucleotide-binding leucine-rich repeat (NLR) receptors ...
Plants deploy cell-surface and intracellular leucine rich-repeat domain (LRR) immune receptors to de...
Plants use both cell surface and intracellular immune receptors with leucine rich-repeat (LRRs) to d...
Arabidopsis pathogen effector-triggered immunity (ETI) is controlled by a family of three lipase-lik...
Plants utilise intracellular nucleotide-binding, leucine-rich repeat (NLR) immune receptors to detec...
Plants encode intracellular immune receptors that detect pathogen effectors and activate defence mec...
Plant intracellular nucleotide-binding/leucine-rich repeat (NLR) immune receptors are activated by p...
The EDS1 family of structurally unique lipase-like proteins EDS1, SAG101, and PAD4 evolved in seed p...
Heterodimeric complexes incorporating the lipase-like proteins EDS1 with PAD4 or SAG101 are central ...
In both plants and animals, nucleotide-binding leucine-rich repeat (NLR) receptors play crucial role...
Plant nucleotide-binding leucine-rich repeat-containing (NLR) receptors with an N-terminal Toll/ int...
Effector-triggered immunity (ETI) in plants involves a large family of nucleotide-binding leucine-ri...
Heterodimeric complexes incorporating the lipase-like proteins EDS1 with PAD4 or SAG101 are central ...
International audienceHeterodimeric complexes containing the lipase-like protein ENHANCED DISEASE SU...
Plants use a complex receptor-based immune system to resist pathogen attacks. Intracellular NUCLEOTI...
Plant pathogen-activated immune signaling by nucleotide-binding leucine-rich repeat (NLR) receptors ...
Plants deploy cell-surface and intracellular leucine rich-repeat domain (LRR) immune receptors to de...
Plants use both cell surface and intracellular immune receptors with leucine rich-repeat (LRRs) to d...
Arabidopsis pathogen effector-triggered immunity (ETI) is controlled by a family of three lipase-lik...