Change over time of COVID-19 hospital presentation in Northern Italy
- Patti G.
- Mennuni M.
- Della Corte F.
- Spinoni E.
- Sainaghi P. P.
- COVID-UPO Clinical Team
- Azzolina D
- Hayden E
- Rognon A
- Grisafi L
- Colombo C
- Lio V
- Pirisi M
- Vaschetto R
- Aimaretti G
- Krengli M
- Avanzi GC
- Balbo PE
- Capponi A
- Castello LM
- Bellan M
- Malerba M
- Garavelli PL
- Zeppegno P
- Savoia P
- Chichino G
- Olivieri C
- Re R
- Maconi A
- Comi C
- Roveta A
- Bertolotti M
- Carriero A
- Betti M
- Mussa M
- Borrè S
- Cantaluppi V
- Cantello R
- Bobbio F
- GavellI F.
DOIAbstract
After the first autochthonous case described on February 19, also in Italy the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARSCoV-2) infection rapidly circulated, mainly in the Northern regions of the country. The earliest reports on Coronavirus disease-19 (COVID-19) have described worldwide a high prevalence of severe respiratory illness [1]. A suggestive feature of COVID-19 has been a rapid progression of the respiratory impairment, leading to acute respiratory distress syndrome (ARDS) and often requiring ventilation support [2]. To date, whether clinical features at hospital presentation and outcome of COVID-19 have changed over the outbreak course is unknown. We explored this issue in a multicenter cohort of patients hospi...
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