Sporadic Burkitt lymphoma (BL) is the most frequent tumour of children and adolescents but a rare subtype of lymphomas in adults. To date most molecular data have been obtained from lymphomas arising in the young. Recently, Epstein-Barr virus (EBV) positive and negative BL in young patients was shown to differ in molecular features. In the present study, we present a large age-overarching cohort of sporadic BL (n = 162) analysed by immunohistochemistry, translocations of MYC proto-oncogene, basic helix-loop-helix transcription factor (MYC), B-cell leukaemia/lymphoma 2 (BCL2) and B-cell leukaemia/lymphoma 6 (BCL6) and by targeted sequencing. We illustrate an age-associated inter-tumoral molecular heterogeneity in this disease. Mutations affe...
Epstein-Barr virus (EBV)-related lymphoproliferative disorders are relatively common in Iraqi childr...
Background: The discovery of Epstein–Barr virus (EBV) in Burkitt lymphoma tumors represented the fir...
Burkitt lymphoma (BL) is the most common B-cell lymphoma in children. Within the International Cance...
Sporadic Burkitt lymphoma (BL) is the most frequent tumour of children and adolescents but a rare su...
Dysregulation of MYC is the genetic hallmark of Burkitt lymphoma (BL) but it is encountered in other...
Dysregulation of MYC is the genetic hallmark of Burkitt lymphoma (BL) but it is encountered in other...
Background: Non-Hodgkin lymphoma is the fourth most common malignant tumors in children, Burkitt lym...
Endemic Burkitt lymphoma (eBL) is primarily found in children in equatorial regions and represents t...
Burkitt's lymphoma (BL) can often be cured by intensive chemotherapy, but the toxicity of such thera...
Burkitt lymphoma (BL) accounts for the majority of pediatric non-Hodgkin lymphomas being less common...
Endemic Burkitt lymphoma (eBL) is the most common pediatric cancer in malaria-endemic equatorial Afr...
Diffuse large B-cell lymphoma is the most frequent type of B-cell lymphoma in adult patients but als...
Burkitt lymphoma (BL) accounts for most pediatric non-Hodgkin lymphomas, being less common but signi...
The exact worldwide incidence of Burkitt's lymphoma is not known. There are three distinct clinical ...
Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (EBV+ DLBCL) is typically an aggress...
Epstein-Barr virus (EBV)-related lymphoproliferative disorders are relatively common in Iraqi childr...
Background: The discovery of Epstein–Barr virus (EBV) in Burkitt lymphoma tumors represented the fir...
Burkitt lymphoma (BL) is the most common B-cell lymphoma in children. Within the International Cance...
Sporadic Burkitt lymphoma (BL) is the most frequent tumour of children and adolescents but a rare su...
Dysregulation of MYC is the genetic hallmark of Burkitt lymphoma (BL) but it is encountered in other...
Dysregulation of MYC is the genetic hallmark of Burkitt lymphoma (BL) but it is encountered in other...
Background: Non-Hodgkin lymphoma is the fourth most common malignant tumors in children, Burkitt lym...
Endemic Burkitt lymphoma (eBL) is primarily found in children in equatorial regions and represents t...
Burkitt's lymphoma (BL) can often be cured by intensive chemotherapy, but the toxicity of such thera...
Burkitt lymphoma (BL) accounts for the majority of pediatric non-Hodgkin lymphomas being less common...
Endemic Burkitt lymphoma (eBL) is the most common pediatric cancer in malaria-endemic equatorial Afr...
Diffuse large B-cell lymphoma is the most frequent type of B-cell lymphoma in adult patients but als...
Burkitt lymphoma (BL) accounts for most pediatric non-Hodgkin lymphomas, being less common but signi...
The exact worldwide incidence of Burkitt's lymphoma is not known. There are three distinct clinical ...
Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (EBV+ DLBCL) is typically an aggress...
Epstein-Barr virus (EBV)-related lymphoproliferative disorders are relatively common in Iraqi childr...
Background: The discovery of Epstein–Barr virus (EBV) in Burkitt lymphoma tumors represented the fir...
Burkitt lymphoma (BL) is the most common B-cell lymphoma in children. Within the International Cance...