BackgroundRecurrent vulvovaginal candidiasis (RVVC) is a problematic form of mucosal Candida infection, characterized by repeated episodes per year. Candida albicans is the most common cause of RVVC. Currently, there are no immunotherapeutic treatments for RVVC.MethodsThis exploratory randomized, double-blind, placebo-controlled trial evaluated an immunotherapeutic vaccine (NDV-3A) containing a recombinant C. albicans adhesin/invasin protein for prevention of RVVC.ResultsThe study in 188 women with RVVC (n = 178 evaluable) showed that 1 intramuscular dose of NDV-3A was safe and generated rapid and robust B- and T-cell immune responses. Post hoc exploratory analyses revealed a statistically significant increase in the percentage of symptom-f...
The majority of human Candida infections occur at a mucosal surface. One of these infections, vulvov...
Recurrent vulvovaginal candidosis (RVVC) is a chronic, difficult to treat vaginal infection, caused ...
Topicality: vulvovaginal candidiasis (VVC) is a common disease caused by the infectious damage of th...
BackgroundRecurrent vulvovaginal candidiasis (RVVC) is a problematic form of mucosal Candida infecti...
Candidemia is a bloodstream fungal infection caused by Candida species and is most commonly observed...
Candidiasis is the most common fungal infection predominantly affecting the mucous membrane. The fun...
We have previously reported that vaccination with rAls3p-N protein of Candida albicans, formulated w...
AbstractVulvovaginal candidiasis (VVC) affects a significant number of women, especially in working ...
<p>A Phase 1b/2a clinical trial of NDV-3A vaccine containing a Candida albicans recombinant Als3 pro...
A Phase 1b/2a clinical trial of NDV-3A vaccine containing a Candida albicans recombinant Als3 protei...
The commensal fungus Candida albicans causes mucosal candidiasis in the rapidly expanding number of ...
A Phase 1b/2a clinical trial of NDV-3A vaccine containing a Candida albicans recombinant Als3 protei...
Vulvovaginal candidiasis is an urgent medical and social problem, a common reason for women to see a...
Vulvovaginal candidiasis (VVC) is a widespread vaginal infection primarily caused by Candida albican...
Vulvovaginal candidiasis infections are estimated to occur at least once during the lifetime of 75% ...
The majority of human Candida infections occur at a mucosal surface. One of these infections, vulvov...
Recurrent vulvovaginal candidosis (RVVC) is a chronic, difficult to treat vaginal infection, caused ...
Topicality: vulvovaginal candidiasis (VVC) is a common disease caused by the infectious damage of th...
BackgroundRecurrent vulvovaginal candidiasis (RVVC) is a problematic form of mucosal Candida infecti...
Candidemia is a bloodstream fungal infection caused by Candida species and is most commonly observed...
Candidiasis is the most common fungal infection predominantly affecting the mucous membrane. The fun...
We have previously reported that vaccination with rAls3p-N protein of Candida albicans, formulated w...
AbstractVulvovaginal candidiasis (VVC) affects a significant number of women, especially in working ...
<p>A Phase 1b/2a clinical trial of NDV-3A vaccine containing a Candida albicans recombinant Als3 pro...
A Phase 1b/2a clinical trial of NDV-3A vaccine containing a Candida albicans recombinant Als3 protei...
The commensal fungus Candida albicans causes mucosal candidiasis in the rapidly expanding number of ...
A Phase 1b/2a clinical trial of NDV-3A vaccine containing a Candida albicans recombinant Als3 protei...
Vulvovaginal candidiasis is an urgent medical and social problem, a common reason for women to see a...
Vulvovaginal candidiasis (VVC) is a widespread vaginal infection primarily caused by Candida albican...
Vulvovaginal candidiasis infections are estimated to occur at least once during the lifetime of 75% ...
The majority of human Candida infections occur at a mucosal surface. One of these infections, vulvov...
Recurrent vulvovaginal candidosis (RVVC) is a chronic, difficult to treat vaginal infection, caused ...
Topicality: vulvovaginal candidiasis (VVC) is a common disease caused by the infectious damage of th...