BackgroundThe apolipoprotein E (APOE) epsilon2 allele has been suggested as having a protective effect and delaying the age at onset of Alzheimer disease.ObjectiveTo describe a dissociation between neuropathologic findings with normal cognition in a woman with severe Alzheimer disease with the APOE epsilon2/epsilon2 genotype.DesignCase report from a community-based prospective study of persons 90 years or older (The 90+ Study).ParticipantA 92-year-old woman without dementia with the APOE epsilon2/epsilon2 genotype who lived independently without significant cognitive or functional loss and was a participant in The 90+ Study. She died in December 2004, and postmortem examination of her brain was performed.InterventionNeurologic examination a...
BACKGROUND:The risk of Alzheimer's disease (AD) appears to increase, and the age at onset to decreas...
BACKGROUND:The risk of Alzheimer's disease (AD) appears to increase, and the age at onset to decreas...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
BackgroundThe apolipoprotein E (APOE) epsilon2 allele has been suggested as having a protective effe...
BackgroundMany studies have examined the role of APOE genotype in the development of dementia, speci...
BackgroundMany studies have examined the role of APOE genotype in the development of dementia, speci...
The objective of this study was to describe a case of Alzheimer\u27s disease in an ApoE epsilon2/eps...
Aims: Apolipoprotein E (APOE) genotype is the major genetic risk factor for sporadic Alzheimer's dis...
Aims: Apolipoprotein E (APOE) genotype is the major genetic risk factor for sporadic Alzheimer's dis...
Aims: apolipoprotein E (APOE) genotype is the major genetic risk factor for sporadic Alzheimer's dis...
In an elderly population of 4,932 that included 694 subjects aged 85 and older, we studied the occur...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
BACKGROUND:The risk of Alzheimer's disease (AD) appears to increase, and the age at onset to decreas...
BACKGROUND:The risk of Alzheimer's disease (AD) appears to increase, and the age at onset to decreas...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
BackgroundThe apolipoprotein E (APOE) epsilon2 allele has been suggested as having a protective effe...
BackgroundMany studies have examined the role of APOE genotype in the development of dementia, speci...
BackgroundMany studies have examined the role of APOE genotype in the development of dementia, speci...
The objective of this study was to describe a case of Alzheimer\u27s disease in an ApoE epsilon2/eps...
Aims: Apolipoprotein E (APOE) genotype is the major genetic risk factor for sporadic Alzheimer's dis...
Aims: Apolipoprotein E (APOE) genotype is the major genetic risk factor for sporadic Alzheimer's dis...
Aims: apolipoprotein E (APOE) genotype is the major genetic risk factor for sporadic Alzheimer's dis...
In an elderly population of 4,932 that included 694 subjects aged 85 and older, we studied the occur...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...
BACKGROUND:The risk of Alzheimer's disease (AD) appears to increase, and the age at onset to decreas...
BACKGROUND:The risk of Alzheimer's disease (AD) appears to increase, and the age at onset to decreas...
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) eps...