We consider a spatial (line) model for invasion of a population by a single mutant with a stochastically selectively neutral fitness landscape, independent from the fitness landscape for nonmutants. This model is similar to those considered earlier. We show that the probability of mutant fixation in a population of size (Formula presented.), starting from a single mutant, is greater than (Formula presented.), which would be the case if there were no variation in fitness whatsoever. In the small variation regime, we recover precise asymptotics for the success probability of the mutant. This demonstrates that the introduction of randomness provides an advantage to minority mutations in this model, and shows that the advantage increases with t...
A mutator is an allele that increases the mutation rate throughout the genome by disrupting some asp...
Abstract. We consider a fitness-structured population model with competition and migration between n...
The role of mutation rate in optimizing key features of evolutionary dynamics has recently been inve...
Fixation probability, the probability that the frequency of a newly arising mutation in a population...
Abstract We consider a simple model of a one-locus, two-allele population inhibiting a two-patch sys...
The evolution of natural organisms is ultimately driven by the invasion and possible fixation of mut...
Numerous experimental studies have demonstrated that the microenvironment is a key regulator influen...
We study the fixation probability of a mutant type when introduced into a resident population. As op...
<p>(a) Random distribution of two types of sites with high and low fitness’s for mutant cells. (b) E...
Mutational robustness quantifies the effect of random mutations on fitness. When mutational robustne...
The role of mutation rate in optimizing key features of evolutionary dynamics has recently been inve...
Replicators such as parasites invading a new host species, species invading a new ecological niche, ...
We study the evolution of a finite size population formed by mutationally isolated lineages of error...
Replicators such as parasites invading a new host species, species invading a new ecological niche, ...
Natural selection is usually studied between mutants that differ in reproductive rate, but are subje...
A mutator is an allele that increases the mutation rate throughout the genome by disrupting some asp...
Abstract. We consider a fitness-structured population model with competition and migration between n...
The role of mutation rate in optimizing key features of evolutionary dynamics has recently been inve...
Fixation probability, the probability that the frequency of a newly arising mutation in a population...
Abstract We consider a simple model of a one-locus, two-allele population inhibiting a two-patch sys...
The evolution of natural organisms is ultimately driven by the invasion and possible fixation of mut...
Numerous experimental studies have demonstrated that the microenvironment is a key regulator influen...
We study the fixation probability of a mutant type when introduced into a resident population. As op...
<p>(a) Random distribution of two types of sites with high and low fitness’s for mutant cells. (b) E...
Mutational robustness quantifies the effect of random mutations on fitness. When mutational robustne...
The role of mutation rate in optimizing key features of evolutionary dynamics has recently been inve...
Replicators such as parasites invading a new host species, species invading a new ecological niche, ...
We study the evolution of a finite size population formed by mutationally isolated lineages of error...
Replicators such as parasites invading a new host species, species invading a new ecological niche, ...
Natural selection is usually studied between mutants that differ in reproductive rate, but are subje...
A mutator is an allele that increases the mutation rate throughout the genome by disrupting some asp...
Abstract. We consider a fitness-structured population model with competition and migration between n...
The role of mutation rate in optimizing key features of evolutionary dynamics has recently been inve...