MicroRNAs (miRNAs) are small (~22 nucleotides) non-coding RNAs that target and repress messenger RNAs through imperfect base-pairing. First discovered in the nematode Caenorhabditis Elegans (C. elegans) (Lee et al., 1993), the microRNA pathway is conserved in many species ranging from humans to plants and plays important roles regulating genes that are critical for proper development, stress responses, and aging. (Bartel, 2018). An essential component of the microRNA pathway is the Argonaute protein. In Caenorhabditis elegans (C. elegans), the microRNA pathway involves two major Argonautes: Argonaute-like Gene 1 (ALG-1) and ALG-2. By knocking down ALG-1 and ALG-2 at different timepoints, one could shut down the entire microRNA pathway to st...
MicroRNAs (miRNA) are critical regulators of development, cell differentiation, and the stress respo...
2019 Summer.Includes bibliographical references.Caenorhabditis elegans contains twenty-five Argonaut...
In C. elegans, DCR-1 is required for the maturation of both short interfering RNAs ( siRNAs) and mic...
MicroRNAs (miRNAs) are small (~22 nucleotides) non-coding RNAs that target and repress messenger RNA...
MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression through the bi...
microRNAs function in diverse developmental and physiological processes by regulating target gene ex...
microRNAs function in diverse developmental and physiological processes by regulating target gene ex...
Among the set of Argonautes proteins encoded by metazoan genomes, some have conserved amino acids im...
MicroRNAs (miRNAs) comprise a large family of small RNA molecules that post-transcriptionally regula...
<div><p>microRNAs function in diverse developmental and physiological processes by regulating target...
<div><p>The genes <em>alg-1</em> and <em>alg-2</em> (referred to as “<em>alg-1/2</em>”) encode the A...
The genes alg-1 and alg-2 (referred to as "alg-1/2") encode the Argonaute proteins affiliated to the...
RNAi is the process by which double-stranded RNA (dsRNA) induces sequence-specific mRNA degradation....
The genes alg-1 and alg-2 (referred to as "alg-1/2") encode the Argonaute proteins affiliated to the...
SummaryMicroRNAs (miRNAs) are tightly regulated through transcriptional and posttranscriptional mech...
MicroRNAs (miRNA) are critical regulators of development, cell differentiation, and the stress respo...
2019 Summer.Includes bibliographical references.Caenorhabditis elegans contains twenty-five Argonaut...
In C. elegans, DCR-1 is required for the maturation of both short interfering RNAs ( siRNAs) and mic...
MicroRNAs (miRNAs) are small (~22 nucleotides) non-coding RNAs that target and repress messenger RNA...
MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression through the bi...
microRNAs function in diverse developmental and physiological processes by regulating target gene ex...
microRNAs function in diverse developmental and physiological processes by regulating target gene ex...
Among the set of Argonautes proteins encoded by metazoan genomes, some have conserved amino acids im...
MicroRNAs (miRNAs) comprise a large family of small RNA molecules that post-transcriptionally regula...
<div><p>microRNAs function in diverse developmental and physiological processes by regulating target...
<div><p>The genes <em>alg-1</em> and <em>alg-2</em> (referred to as “<em>alg-1/2</em>”) encode the A...
The genes alg-1 and alg-2 (referred to as "alg-1/2") encode the Argonaute proteins affiliated to the...
RNAi is the process by which double-stranded RNA (dsRNA) induces sequence-specific mRNA degradation....
The genes alg-1 and alg-2 (referred to as "alg-1/2") encode the Argonaute proteins affiliated to the...
SummaryMicroRNAs (miRNAs) are tightly regulated through transcriptional and posttranscriptional mech...
MicroRNAs (miRNA) are critical regulators of development, cell differentiation, and the stress respo...
2019 Summer.Includes bibliographical references.Caenorhabditis elegans contains twenty-five Argonaut...
In C. elegans, DCR-1 is required for the maturation of both short interfering RNAs ( siRNAs) and mic...