Add to ORKGIn vivo modeling combined with CRISPR/Cas9-mediated somatic genome editing has contributed to elucidating the functional importance of specific genetic alterations in human tumors. Our recent work uncovered tumor suppressor pathways that affect EGFR-driven lung tumor growth and sensitivity to tyrosine kinase inhibitors and reflect the mutational landscape and treatment outcomes in the human disease
Non-small cell lung cancers (NSCLC) with epidermal growth factor receptor (EGFR) gene mutations can ...
Cancer genotyping has identified a large number of putative tumor suppressor genes. Carcinogenesis i...
Comprehensive characterization of the genomic landscape of epidermal growth factor receptor (EGFR)-m...
In vivo modeling combined with CRISPR/Cas9-mediated somatic genome editing has contributed to elucid...
In lung adenocarcinoma, oncogenic EGFR mutations co-occur with many tumor suppressor gene alteration...
Cancer is a multistep process that involves mutations and other alterations in oncogenes and tumor s...
To understand the role of human epidermal growth factor receptor (hEGFR) kinase domain mutations in ...
: Epidermal Growth Factor Receptor (EGFR) enacts major roles in the maintenance of epithelial tissue...
SummaryTo understand the role of human epidermal growth factor receptor (hEGFR) kinase domain mutati...
Epidermal growth factor receptor (EGFR) mutations are the molecular driver of a subset of non-small ...
To discover new tumor suppressor genes (TSGs), we developed a functional genomics approach in which ...
Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer that remains among the m...
Cancer is a genetic disease and this concept is now widely exploited by both scientists and clinicia...
SummaryCancer is a genetic disease and this concept is now widely exploited by both scientists and c...
Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in bo...
Non-small cell lung cancers (NSCLC) with epidermal growth factor receptor (EGFR) gene mutations can ...
Cancer genotyping has identified a large number of putative tumor suppressor genes. Carcinogenesis i...
Comprehensive characterization of the genomic landscape of epidermal growth factor receptor (EGFR)-m...
In vivo modeling combined with CRISPR/Cas9-mediated somatic genome editing has contributed to elucid...
In lung adenocarcinoma, oncogenic EGFR mutations co-occur with many tumor suppressor gene alteration...
Cancer is a multistep process that involves mutations and other alterations in oncogenes and tumor s...
To understand the role of human epidermal growth factor receptor (hEGFR) kinase domain mutations in ...
: Epidermal Growth Factor Receptor (EGFR) enacts major roles in the maintenance of epithelial tissue...
SummaryTo understand the role of human epidermal growth factor receptor (hEGFR) kinase domain mutati...
Epidermal growth factor receptor (EGFR) mutations are the molecular driver of a subset of non-small ...
To discover new tumor suppressor genes (TSGs), we developed a functional genomics approach in which ...
Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer that remains among the m...
Cancer is a genetic disease and this concept is now widely exploited by both scientists and clinicia...
SummaryCancer is a genetic disease and this concept is now widely exploited by both scientists and c...
Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in bo...
Non-small cell lung cancers (NSCLC) with epidermal growth factor receptor (EGFR) gene mutations can ...
Cancer genotyping has identified a large number of putative tumor suppressor genes. Carcinogenesis i...
Comprehensive characterization of the genomic landscape of epidermal growth factor receptor (EGFR)-m...