This disclosure relates to particles comprising recombinant proteins, pharmaceutical composition comprising the particles, and therapeutic uses related thereto. In certain embodiments, the particles are made by the process of producing recombinant proteins and conjugating the recombinant proteins to form nanoparticles with a linking reagent comprising disulfide bonds. Typically the recombinant protein has a polypeptide of viral, fungal, or bacterial origin such as secreted effector proteins AvrA and YopJ. In certain embodiments, the disclosure relates to treating or preventing autoimmune diseases, cancer, or inflammatory diseases, or conditions such as inflammatory bowel disease (IBD).Emory UniversityGeorgia Tech Research Corporatio
Abstract A growing number of insights on the biology of bacterial inclusion bodies (IBs) have reveal...
The invention provides composition and methods for producing proteins of interest which comprise at ...
Although viruses are simple biological systems, they are capable of evolving highly efficient techni...
This disclosure relates to particles comprising recombinant proteins, pharmaceutical composition com...
Protein nanoparticles were proposed as therapeutic protein or enzyme delivery vehicles. The producti...
In this article, a non-chemical crosslinking method is used to produce pure protein microparticles w...
Herein we report the fabrication of protein (bovine serum albumin, BSA) particles which were rendere...
*S Supporting Information ABSTRACT: Recombinant protein therapeutics have in-creased in number and f...
Recombinant proteins are large and complex molecules, whose therapeutic activity highly depends on t...
International PatentThe present invention relates to a polypeptide with endolysin activity and amino...
Herein, we report the fabrication of protein (bovine serum albumin, BSA) particles which were render...
Since recombinant proteins are widely used in industry and in research, the need for their low-cost ...
Since recombinant proteins are widely used in industry and in research, the need for their low-cost ...
In this article, we report an innovative green chemistry approach for the fabrication of protein mic...
This thesis describes recombinant proteins that have been generated by rational and combinatorial pr...
Abstract A growing number of insights on the biology of bacterial inclusion bodies (IBs) have reveal...
The invention provides composition and methods for producing proteins of interest which comprise at ...
Although viruses are simple biological systems, they are capable of evolving highly efficient techni...
This disclosure relates to particles comprising recombinant proteins, pharmaceutical composition com...
Protein nanoparticles were proposed as therapeutic protein or enzyme delivery vehicles. The producti...
In this article, a non-chemical crosslinking method is used to produce pure protein microparticles w...
Herein we report the fabrication of protein (bovine serum albumin, BSA) particles which were rendere...
*S Supporting Information ABSTRACT: Recombinant protein therapeutics have in-creased in number and f...
Recombinant proteins are large and complex molecules, whose therapeutic activity highly depends on t...
International PatentThe present invention relates to a polypeptide with endolysin activity and amino...
Herein, we report the fabrication of protein (bovine serum albumin, BSA) particles which were render...
Since recombinant proteins are widely used in industry and in research, the need for their low-cost ...
Since recombinant proteins are widely used in industry and in research, the need for their low-cost ...
In this article, we report an innovative green chemistry approach for the fabrication of protein mic...
This thesis describes recombinant proteins that have been generated by rational and combinatorial pr...
Abstract A growing number of insights on the biology of bacterial inclusion bodies (IBs) have reveal...
The invention provides composition and methods for producing proteins of interest which comprise at ...
Although viruses are simple biological systems, they are capable of evolving highly efficient techni...