Equipment of renewable energy systems are being supported by Prognostics & Health Management (PHM) capabilities to estimate their current health state and predict their Remaining Useful Life (RUL). The PHM health state estimates and RUL predictions can be used for the optimization of the systems Operation and Maintenance (O&M). This is an ambitious and challenging task, which requires to consider many factors, including the availability of maintenance crews, the variability of energy demand and production, the influence of the operating conditions on equipment performance and degradation and the long time horizons of renewable energy systems usage. We develop a novel formulation of the O&M optimization as a sequential decision p...