The preservation of architectural heritage against earthquakes is currently a topic of increasing interest in Italy and requires an accurate seismic response assessment of the structures. Recent Italian seismic events have shown that severe damage or partial collapse can be caused to historical buildings even by low-to-moderate intensity earthquakes. Structural analysis is a fundamental tool to better evaluate the seismic response and vulnerability of historical buildings and define effective strengthening interventions: in particular, the use of advanced numerical tools to perform three-dimensional (3D) nonlinear dynamic analyses allows obtaining a thorough detailed knowledge of the seismic behavior of such a typology of structures. This c...