The performance of lifelines under damage and emergency conditions induced by sudden extreme events, such as earthquakes, can be assessed based on the concept of resilience. Damage also arises in time due to aging, affecting the structural performance of each network component and, consequently, impairing the overall system functionality. Furthermore, the sparse location over the network of vulnerable deteriorating structures, such as spatially distributed bridges, should be taken into account to establish proper infrastructure management policies. In this article, a probabilistic approach is proposed to assess the seismic performance of transportation networks considering the uncertainties involved in the lifetime structural response of ag...