In this work the 3DCell method has been extended to the thermo-fluid dynamic simulation of an automotive turbocharger's compressor. The 3DCell, an approach continuously developed by the authors at Politecnico di Milano, is based on a pseudo-staggered leapfrog method that allows to decompose a generic 3D problem in a set of 1D scalar equation arbitrarily oriented in space. The system of equations has been solved referring to a relative rotating framework for the moving components, whereas to an absolute reference elsewhere. The domain has been discretized on a basis of a polar coordinate system, identifying five macro sub-domains, namely the inlet pipe, impeller, vaneless diffuser, volute, outlet pipe, each treated numerically in a specific ...