Comorbidity status of deceased COVID-19 in-patients in Italy
- Vetrano D. L.
- Tazzeo C.
- Palmieri L.
- Marengoni A.
- Zucchelli A.
- Lo Noce C.
- Onder G.
- Andrianou X.
- Barbariol P.
- Bella A.
- Bellino S.
- Benelli E.
- Bertinato L.
- Boros S.
- Brambilla G.
- Calcagnini G.
- Canevelli M.
- Castrucci M. R.
- Censi F.
- Ciervo A.
- Colaizzo E.
- D'Ancona F.
- Del Manso M.
- Di Benedetto C.
- Donfrancesco C.
- Fabiani M.
- Facchiano F.
- Filia A.
- Floridia M.
- Galati F.
- Giuliano M.
- Grisetti T.
- Kodra Y.
- Langer M.
- Lega I.
- Lo Noce C.
- Maiozzi P.
- Malchiodi Albedi F.
- Manno V.
- Martini M.
- Urdiales A. M.
- Mattei E.
- Meduri C.
- Meli P.
- Minelli G.
- Nebuloni M.
- Nistico L.
- Nonis M.
- Palmisano L.
- Petrosillo N.
- Pezzotti P.
- Pricci F.
- Punzo O.
- Puro V.
- Raparelli V.
- Rezza G.
- Riccardo F.
- Rota M. C.
- Salerno P.
- Serra D.
- Siddu A.
- Stefanelli P.
- Tamburo de Bella M.
- Tiple D.
- Unim B.
- Vaianella L.
- Vanacore N.
- Vichi M.
- Villani E. R.
- Zona A.
- Brusaferro S.
DOIAbstract
Background: Most COVID-19-related deaths have occurred in older persons with comorbidities. Specific patterns of comorbidities related to COVID-19 deaths have not been investigated. Methods: A random sample of 6085 individuals in Italy who died in-hospital with confirmed COVID-19 between February and December 2020 were included. Observed to expected (O/E) ratios of disease pairs were computed and logistic regression models were used to determine the association between disease pairs with O/E values ≥ 1.5. Results: Six pairs of diseases exhibited O/E values ≥ 1.5 and statistically significant higher odds of co-occurrence in the crude and adjusted analyses: (1) ischemic heart disease and atrial fibrillation, (2) atrial fibrillation and heart ...
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